Expert Pearls
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Cognition - b vitamins - 48855 High dose B-complex vitamin supplementation (B1, B2, B3, B5, B6 (25 mg), B9 and B12) taken in two tablets after breakfast daily in a complex of small doses of vitamins C and E, passion flower and inositol. [Hum Psychopharmacol, 2011 Sept 8; [Epub ahead of print]. 48855 (10/2011)] Summary Interview PubMed |
| Arginine (L-) 400 mg/tab 2 b.i.d. (vascular dementia). [Am J Med, April 1, 2000; 108:439. 34839 (2000)] Summary Interview |
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Cognition - b vitamins - 48248 B Vitamins folic acid 0.8 mg/d, vitamin B12 0.5 mg/d and vitamin B6 20 mg/d. [PLoS One, 2010;5(9):e12244. 48248 (11/2010)] Summary Interview PubMed |
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Cognition - chromium picolinate - 47952 Chromium picolinate as 1000 mcg of elemental chromium in one pill per day with the morning meal. [Nutr Neurosci, 2010; 13(3): 116-22. 47952 (7/2010)] Summary Interview PubMed |
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Cognition - cocoa flavanols - 48676 Cocoa flavanols (CF) 773 mg from specially prepared dark chocolate in a onetime dose away from meals and after breakfast, with avoidances of caffeine, alcohol, and high flavonoid foods for 24 hours. [Physiol Behav, 2011 June 1;103(3-4): 255-60. 48676 (6/2011)] Summary Interview PubMed |
| Creatine at 5 gm qid for 1 week then gms per day. [Dyn Med, 2009 Dec 24; 8(1): 6. Epub ahead of print. 47670 (2/2010)] Summary Interview PubMed |
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Cognition - creatine monohydrate - 45660 Creatine monohydrate 5 gm q.i.d. in elderly benefitted verbal and visual short term memory and long term memory (with or without meals). [Neuropsychol Dev Cogn B Aging Neuropsychol Cogn, 2007;14(5): 517-28. 45660 (1/2008)] Summary Interview |
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Cognition - diet - 43683 / 43803 Dietary intake of folic acid 400 ug/d, vitamin B6 3 mg/d and vitamin B12 10 ug/d slowed or eliminated cognitive decline in elderly. [Am J Clin Nutr. 2005 Sep;82(3):627-35. 43683/43803 (11/2005)] Summary Interview |
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Cognition - homocysteine - 31018 Homocysteine elevation and dietary intake less than folic acid 400 ug/d, vitamin B6 3 mg/d and vitamin B12 10 ug/d increased cognitive decline. [Am J Clin Nutr, 1998;68:1104-10. 31018 (1999)] Summary Interview |
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Cognition - homocysteine - 43803 Homocysteine elevation and dietary intake less than folic acid 400 ug/d, vitamin B6 3 mg/d and vitamin B12 10 ug/d increased cognitive decline. [Am J Clin Nutr. 2005 Sep;82(3):627-35. 43803 (11/2005)] Summary Interview |
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Cognition - hormone replacement therapy - 34054 Hormone replacement therapy (estradiol 1-2 mg/d plus synthetic progestins) reduced risk of cognitive impairment by 64%. [Menopause, 2005;12(1): 12-17. 34054 (5/2005)] Summary |
| Melatonin 3-6 mg (fast-release) at bedtime improved cognitive function in subjects with minimally impaired cognition. [J Pineal Res, 2007; 43(4): 404-409. 45955 (3/2008)] Summary Interview |
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Cognition - nutraceutical combination - 46908 Nutraceutical Combination - Folic acid 400 mcg/d, vitamin E 30 IU/d, vitamin B12 6 mcg/d, S-adenosyl methionine 400mg/d, N-acetylcysteine 600mg/d and acetyl-L-carnitine 500 mg/d in 2 pills per day taken at any time improved cognition and mood. [J Alzheimer's Dis Other Demen, Dec/Jan 2009;23(6):571-585] [ Am J Alzheimer's Dis Other Demen, 2008 Dec 3; [Epub ahead of print]. 46908 (2/2009)] Summary Interview PubMed |
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Cognition - nutraceutical combination - 46908 Nutraceutical Combination - Folic acid 400 mcg/d, vitamin E 30 IU/d, vitamin B12 6 mcg/d, S-adenosyl methionine 400mg/d, N-acetylcysteine 600mg/d and acetyl-L-carnitine 500 mg/d in 2 pills per day taken at any time improved cognition and mood. [J Alzheimer's Dis Other Demen, Dec/Jan 2009;23(6):571-585] [ Am J Alzheimer's Dis Other Demen, 2008 Dec 3; [Epub ahead of print]. 46908 (2/2009)] Summary Interview PubMed |
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Cognition - omega-3 fatty acids, dha, epa - 48773 Omega-3 fatty acids, docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), in the range of 540 mg EPA combined with 360 mg DHA daily showed significant reductions in arterial stiffness. [Am J Clin Nutr, 2011 Feb;93(2):446-54. 48773 (8/2011)] Summary Interview PubMed |
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Cognition - p ycnogenol™- 46830 Pycnogenol™ two 50mg tablets in the morning and one 50 mg tablet in the evening after meals. [J Psychopharmacol, 2008;22(5):553-62. 46830 (12/2008)] Summary |
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Cognition - thyroid function - 45945 Thyroid function - TSH concentrations higher than 2.2 presented lower scores in neurodevelopmental skills, as well as higher risk of attention and hyperactivity/impulsivity symptoms. Higher free T4 levels were associated with a decreased risk of ADHD. [Clin Endocrinol (Oxf), 2007 Jun;66(6):890-8. 45945 (1/2008)] Summary Interview |
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Cognition - vitamin c, vitamin e - 34890 Vitamin C, vitamin E supplements regularly (at least once a week) showed 88% less likely to have vascular dementia and 69% less likely to have forms of dementia other than vascular or Alzheimer’s related dementia or mixed forms of dementia. [Neurology, 2000;54:1265-1272. 34890 (2000)] Summary Interview |
| Walnut containing banana bread equaling two servings (½ cup or 60 g) of ground walnuts (6.80 g of ALA) per day improved inferential verbal reasoning (critical thinking). [Br J Nutr, 2011 Sep 19: 1-9. [Epub ahead of print]. 48953 (1/2012)] Summary Interview PubMed |
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