Expert Pearls
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Hypertension - acetyl-l-carnitine - 47473 Acetyl-L-carnitine - 1 gram B.I.D. on empty stomach before breakfast and 2 hours after dinner. [Hypertension 2009; 54(3): 462-4. 47473 (11/2009)] Summary Interview PubMed |
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Hypertension - beetroot juice - 47417 Beetroot juice 500 ml sipped throughout the day. [J Appl Physiol, August 6, 2009; [Epub ahead of print]. 47417 (10/2009)] Summary Interview PubMed |
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Hypertension - berries - 46352 Berries 1 cup/d (black currants, bilberries, lingonberries and chokeberries, a small amounts of strawberries and raspberries). [Am J Clin Nutr, 2008 Feb;87(2):323-31. 46352 (3/2008)] Summary Interview PubMed |
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Hypertension - bovine casein hydrolysate - 45821 Bovine casein hydrolysate (C12 peptide) 1.9 mg (3 tablets) b.i.d. before breakfast and after dinner reduced blood pressure, plasma angiotensin II and aldosterone. [Am J Hypertens, 2007 Jan; 20(1):1-5. 45821 (3/2008)] Summary Interview PubMed |
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Hypertension - caffeine - 27049 Caffeine intake daily increases blood pressure 2 to 4 mm Hg. [The Lancet, 1997; 349:279-281. 27049 (1997)] Summary Interview PubMed |
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Hypertension - chocolate (dark) - 42904 Chocolate (dark) 100 mg/d (=500 mg polyphenols) reduced systolic BP. [Am J Clin Nutr, 2005;81:611-614. 42904 (04/2005)] Summary Interview |
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Hypertension - coenzyme Q10 - 38689 Coenzyme Q10 60 mg b.i.d. (mean plasma CoQ10 levels increased from about 0.47 mcg/ml to about 2.69 ug/ml with lowering of blood pressure). [S Med J, Nov. 2001;94(11):1112-1116. 38689 (2002)] Summary Interview PubMed |
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Hypertension - dairy products - 23022 Dairy products (low-fat; calcium and angiotensin converting enzyme inhibitory peptides). [Archives of Family Medicine, August 1995;4(8):707-713. 23022 (1996)] Summary Interview PubMed |
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Hypertension - dairy products - 44178 Dairy products (low-fat; calcium and angiotensin converting enzyme inhibitory peptides). [Am J Clin Nutr, 2005 Nov;82(5):972-9. 44178 (12/2005)] Summary Interview PubMed |
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Hypertension - DASH diet - 27062 Diet - DASH diet - COMB - fruit and vegetable consumption was 4 to 5 half-cup servings of each per day and total fat was 25% of the calories - reduced average blood pressure by 5.5 mm Hg, systolic and 3.0 mm Hg, diastolic. [NEJM, April 17, 1997;336:117-24. 27062 (1997)] Summary Interview |
| Diet - increased cereal fiber and vegetable protein. [Arch Med Res, 2006;37(6) :778-86. 44436 (8/2006)] Summary Interview PubMed |
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Hypertension - exercise - 23022 Exercise. [Arch Family Med, August 1995;4:707-713. 23022 (1996)] Summary Interview |
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Hypertension - folic acid - 40185 Folic acid 5 mg/d (lowered BP in smokers). [ J Intern Med, 2002;252:497-503. 40185 (2003)] Summary Interview |
| Garlic powder 300 mg t.i.d. reduced BP > 140 systolic 16/9 mmHg. [Ann Pharmacother, 2008 Nov 18; [Epub ahead of print]. 46837 . (1/2009)] Summary Interview PubMed |
| Aged garlic extract (AGE) in four capsules equaling a daily dose of 960 mg containing 2.4 mg S-allylcysteine with meals and in divided doses if desired. [Maturitas, 2010;67:144-150 48168 (11/2010)] Summary Interview PubMed |
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Hypertension - garlic powder - 46837 Garlic powder 300 mg t.i.d. reduced BP > 140 systolic 16/9 mmHg. [Ann Pharmacother, 2008 Nov 18; [Epub ahead of print]. 46837 (1/2009)]. Summary |
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Hypertension - hibiscus sabdariffa (sour tea) - 46873 Hibiscus Sabdariffa (Sour Tea) tea infusions b.i.d. [J Hum Hypertens, 2008 Aug 7; [Epub ahead of print]. 46873 (4/2009)] Summary Interview PubMed |
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Hypertension - hibiscus sabdariffa tea - 47730 Hibiscus Sabdariffa tea brewed from 1.25 g of dried Hibiscus sadbariffa calyces in one 8 ounce cup (240 mL) of boiled water for 6 minutes consumed 3 times daily hot or cold which can be prepared ahead of time, but should be consumed within 12 hours of preparation. [J Nutr, 2010;140(2):298-303. 47730 (3/2010)] Summary Interview PubMed |
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Hypertension - lifestyle program - 39391 / 43952 Lifestyle Program - DASH II diet or low carbohydrate Mediterranean diet (DASH II diet; 10 servings of fruits, vegetables and whole grains per day; fish 3x per week; lean and low fat meats; increase omega 3 fatty acids, polyunsaturated fatty acids and monounsaturated fatty acids; avoid trans fats in diet; reduce sodium; increase potassium and magnesium; limit alcohol; avoid all tobacco; and limit caffeine); aerobic exercise; weight loss; stress management and nutraceuticals/supplements: CoQ10 60-120 mg/d (antioxidant, free-radical scavenger, ATP production, improve insulin sensitivity); omega 3 FA 30% 3-4 gm/d (anti-inflammatory, anti-arrhythmic, anti-platelet, vasodilatory, lowers fibrinogen); bonita protein 1.5 to 3 grams (ACEI, natriuresis); vitamin B6 100-200 mg/d (improves insulin sensitivity, actions like central alpha agonists, calcium channel blockers, diuretics); hydrolyzed whey protein 30 gm/d (ACEI, natriuresis); R lipoic Acid 200-400 mg/d (increase glutathione, binds aldehydes, normalizes calcium channels, improve insulin sensitivity, increases nitric oxide, improves endothelial function); taurine 2-3 gm/d (diuretic, increased sodium loss, vasodilation, improved insulin sensitivity, increased atrial natriuretic factor); arginine 5-10 gm/day (nitric oxide production, improves endothelial function and insulin sensitivity, regulates cellular Ca2+, Na+, K+); magnesium chelate 500-1000 mg/d (vasodilation, calcium channel blocker); Pycnogenol™ 200 mg/day (ACEI). [Prog Cardiovasc Dis. 2005 May-Jun;47(6):396-449. 39391/43952 (11/2005)] Summary Interview |
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Hypertension - lupin kernel flour - 47008 Lupin kernel flour replacement of 40% of the white, refined flour (higher in protein and fiber) in white bread lowered blood pressure. [Am J Clin Nutr, 2009;89(3):766-772. 47008 (5/2009)] Summary Interview PubMed |
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Hypertension - lyc-o-mato® - 46919 Lyc-O-Mato® 250 mg capsule (15 mg lycopene (6%), β-carotene (0.15%), phytoene and phytofluene (1%) and 5 mg vitamin E (2%), phospholipids (15%) and phytosterol (0.6%) suspended in tomato oleoresin oil;. 15 mg of lycopene ingested can increase serum levels of lycopene of 1 microgram) with main meal. [Cardiovasc Drugs Ther, 2008 Dec 4; [Epub ahead of print]. 46919 (3/2009)] Summary Interview PubMed |
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Hypertension - magnesium - 30585 Magnesium oxide 400 mg b.i.d.. [Hypertension, August 1998;32:260-265. 30585 (1998)] Summary Interview |
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Hypertension - magnesium oxide - 47206 Magnesium oxide - 300 mg per day of elemental magnesium in divided doses. [Nutr Metab Cardiovas Dis, 2009 April 7;[Epub ahead of print]. 47206 (8/2009)] Summary Interview PubMed |
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Hypertension - melatonin - 32203B / 32203 Melatonin 1 mg/d between 2:30 and 5:30 p.m. on two consecutive days lowered blood pressure. [Am J Cardiol, May 1, 1999;83:1417-1418. 32203B/32203 (1999) Summary Interview |
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Hypertension - myo-Inositol - 44653 / 46297 Myo-Inositol 18 gm/d (reduced systolic and diastolic blood pressures by an average of 10 mm Hg). [Cancer Epidemiol Biomarkers Prev, 2006 Aug;15(8):1526-31. 44653/46297 (11/2006)] Summary Interview |
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Hypertension - olive leaf extract - 46631 Olive Leaf Extract, Benolea® (EFLA®943) at 500 mg b.i.d. with meals. [Phytother Res, 2008 Aug; 22(9): 1239-1242. 46631 (9/2008)] Summary Interview |
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Hypertension - omega-3 fatty acids - 24138 / 24131 Omega-3 fatty acids 4 gm/d (EPA/DHA) reduced systolic BP 3.8 mm Hg and diastolic BP 2.0 mm Hg > than controls. [Ann Internal Med, December,1995;123(12):911-918. 24138/24131 (1996)] Summary Interview |
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Hypertension - omega-3 fatty acids - 46407 Omega-3 fatty acids (2 g/d DHA and 3 g/d EPA, fish oil) in 3 divided doses with meals increased stroke volume and cardiac output. [Eur J Appl Physiol, 2008 June 18; [Epub ahead of print]. 46407 (8/2008)] Summary Interview |
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Hypertension - omega-3 fatty acids - 47890 Two grams per day of purified EPA and DHA (not less than 85%) in a 1:1 ratio given as 1 gram with the two main meals significantly reduced systolic and diastolic blood pressures, pulse pressure and basal heart rate. [Clin Exp Hypertens, 2010; 32(2): 137-44. 47890 (5/2010)] Summary Interview PubMed |
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Hypertension - partnership - 44274 Partnership - good partnership reduces blood pressure and loneliness increases blood pressure. [Psychol Aging, 2006;21(1):152-64. 44274 (6/2006)] Summary Interview |
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Hypertension - pet therapy/ownership - 23982 Pet therapy/ownership in elderly patients. [Am J Occupat Therapy, Jan. 1996; 50(1):47-51. 23982 (1997)] Summary Interview |
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Hypertension - phytoestrogens, soy protein - 48527 Soy protein concentrate 30 gms (70% proteins) containing 16 mg of phytoestrogens (54% genistein, 35% daidzein, and 12% glycitein) reduced blood pressure, HS C-reactive protein and insulin resistance and triggered overt hypothyroidism in subclinical hypothyroid patients. [ J Clin Endocrinol Metab, 2011 Feb 16; [Epub ahead of print]. 48527] Summary Interview PubMed |
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Hypertension - quercetin - 45787 Quercetin 365 mg 2 per day with meals. [J Nutr, 2007; 137(11): 2405-11. 45787 (1/2008)] Summary |
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Hypertension - sodium chloride - 23022 Sodium chloride limited to 6 g/d or 100 mmol of sodium = 1 teaspoon of salt. [Arch Family Med, August 1995;4:707-713. 23022 (1996)] Summary Interview |
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Hypertension - soy protein - 45256 Soy protein - 25 gm of soy nuts (½ cup = 101 mg of aglycone isoflanvones). [Arch Int Med, 2007;167:1060-1067; J Womens Health (Larchmt), 2007;16(3): 361-9. 45256 (1/2008)] Summary Interview |
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Hypertension - transcendental meditation - 44410 / 45012 Transcendental Meditation (TM) 2 x per day for 20 minutes each session reduced blood pressure, blood sugar, blood insulin, insulin resistance and heart rate variability improved. [Arch Intern Med, 2006 Jun 12;166(11):1218-24. 44410/45012 (10/2006)] Summary Interview |
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Hypertension - vitamin B6 - 38689 Vitamin B6 200-400 mg/d. [S Med J, Nov. 2001;94(11):1112-1116. 38689 (2002)] Summary Interview |
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Hypertension - watermelon - 48080 Two grams twice daily of watermelon extract with a citrulline:arginine ratio of 2:1 ratio (2.7 g of L-citrulline and 1.3 g of L-arginine) ingested 1 hour before or after meals showed a reduction in aortic blood pressure (BP). [Am J Hypertens, 2010 July 8; [Epub ahead of print]. 48080 (08/2010)] Summary Interview PubMed |
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Hypertension - weight loss - 23022 Weight loss. [Archives of Family Medicine, August 1995;4:707-713. 23022 (1996)] Summary Interview |
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