Current Research Expert Pearls
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Coronary Artery/Heart Disease (see also cardiovascular disease) |
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Erectile Dysfunction - periodontal disease - 50171 Vasculogenic erectile dysfunction (VED) can be affected by chronic periodontitis do to inflammatory cytokines released that can negatively affect endothelial dysfunction of the small vessels in the penis. Diets that are rich in protein, whole grains, fiber, vitamins, minerals and PUFAs have positive effects on periodontal health and can improve endothelial function and reduce vulnerability to VED. [J Periodonto, 2011 Dec;82(12):1665-9. 50171 (4/2013)] Interview PubMed |
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Erectile Dysfunction - propionyl-l-carnitine - 45315 Carnitine - propionyl-l-carnitine (PLC) 1 gm b.i.d. independently from Sildenafil 50 mg b.i.w. and meals in diabetic patients with erectile dysfunction reduced oxidative stress and improved endothelial dysfunction markers in type 2 diabetic patients with erectile dysfunction and had more sustained improvement in symptoms of E.D. than Sildenafil alone. [Eur Urol, 2007 Apr 25; [Epub ahead of print]. 45315 (7/2007)] Summary Interview |
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Erectile Dysfunction - yohimbine - 26601 / 26602 Erectile DysfunctionYohimbine 5-10 mg t.i.d.. [Arch Sexual Behavior, 1997;26(1):49-62. 26601 / 26602 (1997)] Summary Interview |
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Erectile Dysfunction - yohimbine - 39233 Yohimbine 5.4 mg -10.8 mg t.i.d. or 5.4 mg 1-2 tablets 15-30 minutes before sex. [Intern J Impotence Res,2002;14:25-31. 39233 (2002)] Summary Interview |
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Erythema Nodosum - Vitamin B12 Vitamin B12 I.M. 1000 mcg twice a week x 4 weeks then monthly I.M. vitamin B12 1000 mcg. At six months oral sublingual vitamin B12 1000 mcg twice a week (case report of complete remission). [J Am Board Fam Pract. 2005 Nov-Dec;18(6):567-9. 43946/44357 (1/2006)] Summary Interview |
| Folic acid 2.5 mg/d, vitamins B6 50 mg/d and vitamin B12 1 mg/d (in case of concurrent methotrexate therapy supplementation with 15 mg of calcium folinate the day after the administration of methotrexate). [ J Dermatolog Treat, 2007;18(3):138-46. 44991/45996 (11/2007)] Summary Interview |
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Estrogen Metabolism - Dioxin exposure Dioxin exposure may decrease the 2:16 estrogen ratio by increasing16-hydroxyestrogens. [Arch Environ Occup Health, 2005 Jul-Aug;60(4):215-22. 45639 (03/2007)] Summary Interview |
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Exercise - antioxidants - 24460 Antioxidants (beta-carotene, vitamin C, vitamin E) can reduce oxidative damage in heavy exercisers. [Sports Medicine, 1996;21(3):213-238. 24460 (1996)] Summary Interview PubMed |
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Exercise - antioxidants - 34758 Antioxidants - beta-carotene 32 mg/d, vitamin C 1000 mg/d, vitamin E 600 mg/d reduced lipid peroxides and prevented reductions in vitamin C levels in professional basketball players. [Int J Sports Med, 2000;21(2):146-150 . 34758 (2000)] Summary Interview PubMed |
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Exercise - athletes, probiotics - 48851 Lactobacillus rhamnosus and Lactobacillus paracase at 109 cells per day in a powder suspended in water (aqueous suspension) in the morning, during breakfast in a single dose. [ Curr Microbiol, 2011 June; 62(6):1689-96. 48851 (11/2011)] Summary Interview PubMed |
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Exercise - beetroot juice - 47417 Beetroot juice (nitrate rich) 500 ml sipped throughout the day. [J Appl Physiol, August 6, 2009; [Epub ahead of print]. 47417 (10/2009)] Summary Interview PubMed |
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Exercise - beets - nitric oxide - 50122 Beetroot - 200 grams of baked, peeled and chopped beetroot (≥500 mg nitrate), mixed with cinnamon and other herbs for palatability, taken on an empty stomach 45-60 minutes before running. [JAcad Nutr Diet, 2012 Apr;112(4):548-52. 50122 (9/2012)] Interview PubMed |
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Exercise - branch chain amino acids (bcca) - 45547 Branch chain amino acids (BCAA) 6 gms/d in 5 divided doses during the run, an additional 2 grams administrated on the day of 25-km run (2g/500ml; 0.4% mixture of BCAA in a 4% carbohydrate solution) reduced muscle soreness, fatigue and LDH elevation. [J Sports Med Phys Fitness, 2007; 47(3): 316-322. 45547 (12/2007)] Summary Interview PubMed |
| Caffeine 3 mg of caffeine per kilo of body weight (approximately1 to 1½ mugs of strong coffee) as ergogenic aid for endurance and sprint activity. [J Applied Physiol, 1994;19(1):111-138. 20801 (1995)] Summary Interview |
| Carnitine (-L) 3 gm/d reduced DOMS (delayed onset muscle soreness) and CPK levels after eccentric exercise of the quadriceps (20 minute single step test). [Int J Sports Med, 1996;17:320-324. 25588 (1997)] Summary Interview |
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Exercise - citrulline mallate - 47908 Citrulline malate 8 grams one hour before the training session. [J Strength Cond Res, 2010 Apr 7; [Epub ahead of print]. 47908 (6/2010)] Summary Interview PubMed |
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Exercise - coenzyme q10 - 46214 Coenzyme Q10 100mg b.i.d. (1 tablet, “fast-melt”) taken 30 minutes prior to each meal (morning and night). [J Int Sic Sports Nutr, 2008; 5(1): 8. 46214 (7/2008)] Summary |
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Exercise - coenzyme q10 - 47366 Coenzyme Q10 100 mg daily in a single dose every 24 hours in powder-filled capsules in the morning after breakfast increased anaerobic capacity. [J Strength Cond Res, 2009 July 28; [Epub ahead of print]. 47366 (10/2009)] Summary Interview PubMed |
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Exercise - coenzyme q10 - 48741 Coenzyme Q10 100 mg daily in a single dose (powder-filled capsules) in the morning after breakfast for 8 weeks decreased malondialdehyde (oxidative stress) after repeated short-term supramaximal exercise. [ J Sports Med Phys Fitness, 2011 June;51(2):305-12. 48741 (8/2011)] Summary Interview PubMed |
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Exercise - creatine - 28249 / 28621 / 28250 Creatine 20 g/d loading dose x 5 days then 2-5 gm/d (‘sprinting’ type exercises). [Internat J Sports Med, 1997;18:369-372. 28249, 28621/28250 (1997)] Summary Interview |
| Creatine 20 g/d loading dose x 5 days then 2-5 gm/d (‘sprinting’ type exercises). [Clin J Sports Med 1998;8(4):286-297. 32700 (1999)] Summary Interview |
| Creatine 20 g/d loading dose x 5 days then 2-5 gm/d (‘sprinting’ type exercises). [J Sports Med Phys Fitness, 1999;39:189-196. 34329 (2000)] Summary Interview |
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Exercise - disease prevention - 24181B Disease prevention - daily participation in the prescribed exercise program has highly beneficial effects on cardiovascular diseases, diabetes, arthritis, hyperlipidemia, depression, cancer and COPD: a) by increasing blood supply to all organs and tissues; b) by improving muscle/tendon/ ligament/strength, mobility and flexibility; c) by the release of endorphins (the feel good hormones); d) by increasing bone formation; and e) by stimulating creativity. Exercise restores/improves the function of all body tissues and organs. [The Physician and Sports Medicine, February, 1996;24(2):72-78. 24181B (1996)] Summary Interview |
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Exercise - duodenal ulcer - 35844 Duodenal ulcer risk was reduced risk by approximately 50% in males with moderate or higher amounts of leisure-time physical activity (active - those who walked or ran 10 miles or more a week; moderately active - those who walked or ran less than 10 miles a week or did another regular activity). [West J Med, August 2000;173:101-107. 35844 (2000)] Summary Interview |
| Two grams of ground ginger (either “raw” or “heat-treated”) divided into 6 capsules was taken in a single dose orally with water away from meals. [J Pain, 2010 Apr 23; [Epub ahead of print]. 47991 (8/2010)] Summary Interview PubMed |
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Exercise - juice plus® - 44563 Juice Plus® 6 capsules/d (12,500 IU vitamin A activity (100% from beta-carotene), 276 mg vitamin C, 108 IU vitamin E, 780 mcg folate, and 80 mg calcium per day, in addition to other phytonutrients / reduced post-exercise protein carbonyls). [Med Sci Sports Exerc, 2006; 38(6): 1098-105. 44563 (12/2006)] Summary Interview |
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Exercise - lactobacillus paracase, lactobacillus rhamnosus - 48851 Lactobacillus rhamnosus and Lactobacillus paracase at 109 cells per day in a powder suspended in water (aqueous suspension) in the morning, during breakfast in a single dose. [Curr Microbiol, 2011 June; 62(6):1689-96. 48851 (11/2011)] Summary Interview PubMed |
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Exercise - magnesium orotate - 31201 Magnesium orotate 1,000 mg (65.6 mg of elemental magnesium) t.i.d. improved cardiovascular function and exercise tolerance in CHD patients. [Cardiovascular Drugs and Surgery, 1998;12:153-156. 31201 (1999)] Summary Interview |
| Melatonin in 3 mg capsules taken orally, 1 capsule two days before the exercise test with the dinner, 3 capsules on the previous day (breakfast, lunch and dinner), 1capsule one hour before beginning the physical test. [J Pineal Res, 2011 April 21; [Epub ahead of print]. 48703 (6/2011)] Summary Interview PubMed |
| Probiotics (Bifidobacterium bifidum W23, Bifidobacterium lactis W51, Enterococcus faecium W54, Lactobacillus acidophilus W22, Lactobacillus brevis W63, and Lactococcus lactis W58; Ecologic®Performance or OMNi-BiOTiC®POWER) at 2 sachets per day at 2 g each (4g/day), equivalent to1010 CFU/day was taken in 100–125 mL of plain water with one sachet taken one hour prior to meals decreased zonulin levels suggesting improvement in gut barrier integrity. [J Int Soc Sports Nutr, 2012 Sep 20;9(1):45. 49368 (11/2012)] Summary Interview PubMed |
| Ribose 5 g dissolved in water and ingested 30 - 60 minutes before and after weight-training regimen (total of 10 g/d). [Curr Therapeutic Res, August 2002;63(8):486-495. 40023 (2003)] Summary Interview |
| Vitamin C 500 mg/d. [Internat J Vit Nutr Res, 1999;69(1):41-44. 31868 (1999)] Summary Interview |
| Vitamin C 1000 mg/d and vitamin E 400 IU/d (reduced post-exercise protein carbonyls). [Med Sci Sports Exerc, 2006; 38(6): 1098-105. 44563 (12/2006)] Summary Interview |
| Vitamin C 1000 mg/d, vitamin E 400 IU/d and selenium 90 ug/d (reduced post-exercise muscle soreness). [Med Sci Sports Exerc, 2006; 38(6):1098-105. 44563 (12/2006)] Summary Interview |
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Exercise - vitamin c - 44694 / 46287 Vitamin C 1000 mg t.i.d. (pretreatment reduced muscle soreness). [Int J Sport Nutr Exerc Metab, 2006 Jun;16(3):270-80. 44694/46287 (4/2007)] Summary Interview |
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Exercise - vitamin d2, vitamin d3 - 48786 Vitamin D2 or D3 at 50,000 IU given once or twice weekly with breakfast in vitamin D insufficient (<32 ng/ml) hypercholesterolemic subjects suffering from statin-induced myositis-myalgias resulted in resolution of these symptoms with normalization of vitamin D levels (goal 40-80 ng/ml). [Curr Med Res Opin, 2011 July 6; [Epub ahead of print]. 48786 (9/2011)] Summary Interview PubMed |
| Calcium 1,000 mg/d (elemental from calcium carbonate) and vitamin D3 400 IU (10 ug) reduced risk. [Aging Clin Exp Res. 2005 Apr;17(2):125-32. 43407, 43537/43598 (9/2005)] Summary Interview |
| Calcium citrate 1000 mg/d (elemental ) in divided doses with meals and vitamin D2 1000 iu/d with the evening meal. [Arch Intern Med, 2008;168(1):103-8. 46001 (6/2008)] Summary Interview |
| Caffeine withdrawal symptoms in a.m.. [The Lancet, 1997;349:279-281. 27049 (1997)] Summary Interview |
| Diet - eliminate caffeine, sucrose and eat a higher protein and lower carbohydrate diet x 2 weeks. [The Nutrition Report, March 1991;9(3):17,24. 12081 (1996)] Summary Interview |
| Vitamin B12 normal ranges should be 600 to 2000 pg/ml. Below 550 to 600 pg/ml deficiencies start to appear in the CSF. Humans are born with serum levels of about 2000 pg/ml, which decline gradually throughout life. [Medical Hypotheses, 1991;34:131-140. 28725 (1998)] Summary Interview |
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Fatigue - vitamin c, intravenous - 49041 Vitamin C as ascorbic acid alone at 10 grams given over 30 minutes in 100 cc of normal saline improved fatigue in fatigued office workers without side effects. Fatigue symptoms improved within 2 hours and lasted for a day. Vitamin C reduced oxidative stress and increased blood levels of vitamin C. No other nutrients were give with the vitamin C. [ Nutr J. 2012 Jan 20; 11(1):7. 49041 (3/2012)] Summary Interview PubMed |
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Fibrinogen (lowering) - Alcohol Alcohol (moderate); cigarette smoking cessation (significantly reduces); exercise; garlic; omega-3 fatty acid rich diets; vegetarian diet; weight loss. [Arterio, Thromb, Vasc Biol, September, 1995;15(9):1263-1268. 24063 (1996)] Summary Interview |
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Fibrinogen (lowering) - Cardiovascular risk factor Cardiovascular risk factor. [Arterio, Thromb, Vasc Biol, September, 1995;15(9): 1263-1268. 24063 (1996)] Summary Interview |
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Fibrinogen (lowering) - Niacin Niacin: Day 1 0.25 gm after lunch, 0.5 gm after dinner and 0.5 gm at night. Day 2 0.25 gm after breakfast, 0.5 gm after lunch, 0.5 gm after dinner and 1gm at night. Day 3 0.25 gm after breakfast, 0.5 gm after lunch, 1gm after dinner and 1gm at night. Day 4 1gm four times daily, taken immediately after the meals and at bedtime. Niacin therapy: Fibrinogen is lowered by 15%; raises HDL-C by 20- 40%; HDL2-C, the large HDL particle is raised by up to 100%; a negligible effect on smaller HDL3; LDL-C is lowered by 15-30%; small, dense LDL particles are significantly lowered; triglycerides are lowered by 15-40%; and Lp(a) decreases10-40%. [J Intern Med. 2005 Aug;258(2):94-114. 43553 (01/2005)] Summary Interview |
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Fibrinogen (lowering) - omega-3 fatty acids, epa, dha - 48958 Omega-3 fatty acid (EPA and DHA) serum levels are inversely associated with fibrinogen levels. Two fish servings per week approximately 1 gram combined EPA and DHA per day. [Eur J Clin Nutr, 2011 Sep 7; [Epub ahead of print]. 48958 (12/2011)] Summary Interview PubMed |
| Pycnogenol™ 50 mg per tablet taken twice a day, after breakfast and after dinner. [Redox Rep, 2008; 13(6): 271-6. 46883 (3/2009)] Summary Interview PubMed |
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Fibrocystic Breast Disease - omega-3 fatty acid - 46920 Omega-3 fatty acid eicosapentaenoic acid (EPA) elevated in RBC is protective. Am J Clin Nutr, 2009; 89(1): 265-76. 46920 (4/2009) Summary Interview PubMed |
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Fibroids (uterine) - Enterolignans Higher urine levels of enterolignans (lignans) reduce risk of fibroids. [Am J Clin Nutr, 2006 Sep;84(3):587-93. 45305 (2/2007)] Summary Interview |
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Fibromyalgia - coenzyme q10 - 48643 Coenzyme Q10 300 mg/d (soft gel capsules) in three divided doses with meals. [Mitochondrion, 2011 April 7; [Epub ahead of print]. 48643 (5/2011)] Summary Interview PubMed |
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Fibromyalgia - d-ribose - 41201 / 42747 D-ribose at 5 gms t.i.d. with or without meals for approximately 3 weeks (loading dose) then 5 gm b.i.d. for up to six weeks (can stop if no benefit). [Pharmacotherapy, 2004;24(11):1646-1648. 41201/42747 (02/2005)] Summary Interview |
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Fibromyalgia - d-ribose - 44986 / 45599 D-ribose at 5 gms t.i.d. with or without meals for approximately 3 weeks (loading dose) then 5 gm b.i.d. for up to six weeks (can stop if no benefit). [J Altern Complement Med, 2006 Nov;12(9):857-62. 44986/45599 (4/2007)] Summary Interview PubMed |
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Fibrosis (submucous) - lycopene - 49480 Lycopene (soft gel LycoredTM) at 4 mg twice a day with meals ameliorated the signs and symptoms of oral submucous fibrosis (pre-malignant condition) and improved maximal mouth opening percentage with no side effects. [Indian J Dent Res, 2012 July; 23(4): [Epub ahead of print]. 49480 (2/2013)] Summary Interview PubMed |
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Fibrosis - alpha lipoic acid - 48558 Alpha lipoic acid 100 mg after meals once daily for 3 months in conjunction with intralesional steroids and hyaluronidase.[J Cancer Res Ther, 2010 Oct-Dec; 6(4): 508-10. 48558 (04/2011)] Summary Interview PubMed |
| Folic acid fortification may correct nucleotide polymorphisms (SNPs) that may reduce the risk to cardiovascular disease, cancer and birth defects. [BMJ USA, March 2004;4:127-131. 41556 (2004)] Summary Interview |
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Folic acid - Fortification - 2 Folic acid fortification with pteroylmonoglutamic acid (PGA) is not the natural form of the folic acid but is cheap and stable. 5-methyl-H4 folate (5-MTHF) is the major transport form of the vitamin outside the cell. A single dose of 400 mcg (or less) of PGA is converted efficiently into 5-methyl-H4 folate during absorption. The absorption and biotransformation process is saturated at this 400 mcg dose, and anything higher intake will lead to unmodified PGA appearing in the blood which have unknown toxicity. [BMJ USA, March 2004;4:127-131. 41556 (2004)] Summary Interview |
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Fracture (hip) - calcium - vitamin d - 47310 Calcium 500 mg and vitamin D 400 IU once or twice daily improved post-fracture (hip) survival. [Drugs Aging, 2009;26(5):409-21. 47310 (9/2009)] Summary Interview PubMed |
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Fracture (hip) - calcium - vitamin d - 47310 Calcium 500 mg and vitamin D 400 IU once or twice daily improved post-fracture (hip) survival. [Drugs Aging, 2009;26(5):409-21. 47310 (9/2009)] Summary Interview PubMed |
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Fracture (hip) - risk factors - 22016 Risk factors - bisphosphonates, caffeine, estrogen therapy, exercise lack, frailty, hip fracture previously, medications (sedatives, hypnotics), visual impairment. [NEJM, March 25, 1995;12:767-773. 22016 (1996)] Summary Interview PubMed |
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Fracture (hip) - sunlight exposure - 43486 Sunlight exposure (3615 minutes/year or 10 minutes/d) in hospitalized Alzheimer’s patients over 1 year reduced fractures and increased vitamin D levels 2.2 fold. [J Bone Mineral Res, 2005;20(8):1327-1333. 43486 (8/2005)] Summary Interview PubMed |
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Fracture (hip) - vitamin d2 - 43662 / 43704 Vitamin D2 (ergocalciferol) 1000 IU/d, vitamin K2 (menatetrenone) 45 mg/d and calcium 600 mg/d (reduced incidence). [Bone. 2005 Jan;36(1):61-8. Epub 2004 Nov 24. 43662/43704 (9/2005)] Summary Interview PubMed |
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Fragile X Syndrome (FXS) - Acetyl-L-carnitine Acetyl-L-carnitine 20-50 mg/kg/d b.i.d. in granular form dissolved in water or other liquids with or without meals. [Am J Med Genet A, 2008; 146(7): 803-12. 46191 (7/2008)] Summary Interview |
| Melatonin, L-tryptophan, vitamin B6, vitamin B12, folic acid, methionine and betaine in a single dose after dinner. [J Pineal Res, 2006 Oct;41(3):195-200. 44812/45346 (11/2006)] Summary Interview |
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Genital (warts) - vitamin c, pidotimod - 48287 Vitamin C (1000 mg/per day) plus Pidotimod at 800 mg (2 sachets/day) was given for 15 days by mouth after laser vaporization surgery for genital warts, then for two months post-surgery vitamin C at 500 mg per day and Pidotimod 1 sachet per day (400 mg) was taken. [J Med Life, 2010 July-Sept;3(3):286-8. 48287 (12/2010)] Summary Interview PubMed |
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Gestational Diabetes - probiotic - lactobacillus rhamnosus gg - bifidobacterium lactis bb12 - 47769 Probiotics Lactobacillus rhamnosus GG and Bifidobacterium lactis Bb12 at 1010 CFU per day of each strain in capsules given once daily in healthy pregnant females from the first trimester through the end of exclusive breast feeding was safe and reduced the incidence of gestational diabetes. [ Br J Nutr., 2010 Feb 4:1-8. [Epub ahead of print]. 47769 (4/2010)] Summary Interview PubMed |
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Gingivitis (see also periodontal disease) - LycoRed™ LycoRed™ (100% natural lycopene with added phytoene, phytofluene, carotene, phytosterols, vitamin E) 8 mg/d in four divided doses of 2 mg in soft gels before meals. [Oral Health Prev Dent, 2007; 5(4): 327-36. 46229 (6/2008)] Summary Interview |
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Glaucoma - fruit, vegetables - 49315 Diet - 3 or more servings per week of fruit/fruit juices; collard greens/kale more than once per week; eating more oranges and peaches; and higher intakes of vitamins A, C and alpha-carotene reduce glaucoma risk. [Am J Ophthalmol, 2012 Jul 19; [Epub ahead of print]. 49315 (10/2012)] Summary Interview PubMed |
| Vitamin C intake was inversely associated in a dose-response fashion with serum uric acid concentrations and a lower likelihood of having hyperuricemia up to levels of 400-500 mg/day of vitamin C. [J Rheumatol, 2008 May 1; [Epub ahead of print]. 46286 (7/2008)] Summary Interview |
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Grave’s Disease - Antioxidant mixture Grave’s Disease Antioxidant mixture - vitamin C 250 mg, vitamin E 200 mg, β-carotene 3 mg, Cu 1 mg, Zn 7.5 mg, Mn 1.5 mg and Se 15 μg/d. [Clin Chim Acta,. 2005 Feb;352(1-2):115-20/ IUBMB Life, 2001;51:105-109. 38568 (2002)] Summary Interview |
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Grave’s Ophthalmopathy - Antioxidant therapy Antioxidant therapy - allopurinol 300 mg/d and nicotinamide 300 mg/d orally. [Am J Ophthalmol, 2000;129:618 -622. 35396 (2001)] Summary |
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Growth and Development - Juice Juice (fruit) was inversely relate to stature. [J Am Coll Nutr 1999;18(4):346-352. 32670 (1999)] Summary Interview |
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Halitosis (bad breath) - Green tea powder Green tea powder 675 mg/d poured on the tongue and allowed to dissolve in saliva, and then naturally swallowed. [J Nutr Sci Vitaminol, 2008;54(1):89-94. 46357 (06-13-08)] ltt Summary |
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Halitosis - korea red ginseng - 47477 Korea red ginseng 300 mg three times daily with H. Pylori eradication. [Digestion, 2009;80(3):192-199. 47477 (11/2009)] Summary Interview PubMed |
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HDL Cholesterol (elevating) - alpha lipoic acid - 47306 Alpha lipoic acid 400 mg/d. [Aging Clinical and Experimental Research, 2009;21(2):198. 47306 (10/2009)] Summary Interview PubMed |
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HDL Cholesterol (elevating) - amla - 46846 Amla (Emblica Officinalis Extract, Amlamax) at 500-1000 mg/d at bedtime with food. [Indian J Clin Biochem, 2008; 23(4): 378-381. 46846 (2/2009)] Summary Interview |
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HDL Cholesterol (elevating) - anthocyanins - 47395 Anthocyanins 160 mg b.i.d. [Am J Clin Nutr, 2009;90(3):485-92. 47395 (11/2009)] Summary Interview PubMed |
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HDL Cholesterol (elevating) - apoa5 - diet - fat - gene - 50143 Diet – high fat diet (40%) may be more effective in raising HDL cholesterol in those with the gene polymorphism APOA5 rs964184 with the G allele than those who don’t. [Am J Clin Nutr, 2012 Oct; 96(4):917-22. Epub 2012 Aug 22. 50143 (11/2012)] Interview PubMed |
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HDL Cholesterol (elevating) - berries - 46352 Berries 1 cup/d (black currants, bilberries, lingonberries and chokeberries, a small amounts of strawberries and raspberries). [Am J Clin Nutr, 2008 Feb;87(2):323-31. 46352 (3/2008)] Summary Interview |
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HDL Cholesterol (elevating) - combination therapy - 46916 Combination Therapy - Niaspan® 500-1500 mg/d at dinner-time; EPA + DHA mean dose of 1440 mg/d in a divided dose with breakfast and dinner; vitamin D 3590 IU/d (25-hydroxy vitamin D of 50-60 nag/ml) in gel cap form; and the American Heart Association Step II diet with 30% of calories from fat, ≤7% from saturated fat either stopped or reversed calcium scores. The goal was to get LDL < 60, HDL > 60 and triglycerides < 60 with the above approach. There was marked improvement in this program with the addition of vitamin D. [Am J Ther, 2008 Dec 15; [Epub ahead of print]. 46916 (3/2009)] Summary Interview PubMed |
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HDL Cholesterol (elevating) - egg yolks - 47554 Egg yolks 2-4/d increased HDL. [Am J Clin Nutr, 2009; 90(5): 1272-9. 47554 (12/2009)] Summary Interview PubMed |
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HDL Cholesterol (elevating) - garlic - 45121 Garlic - one enteric-coated garlic powder tablet (equal to 400 mg garlic, 1 mg allicin) twice daily with meals. [Lipids Health Dis, 2007 Mar 1; [Epub ahead of print]. 45121 (5/2007)] Summary |
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HDL Cholesterol (elevating) - green tea, pomegranate, vitamin c - 47602 PomGT tablet (pomegranate extract (500 mg), green tea extract (300 mg) and vitamin C (60 mg) per tablet) 1 capsule 2 hours after dinner. [J Endocrinol Invest, 2009 Oct 15; (DOI: 10.3275/6564 ) [Epub ahead of print] 47602 (01/2010)] Summary Interview PubMed |
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HDL Cholesterol (elevating) - kale juice - 46391 Kale juice -150 mL of pure kale juice given in a single dose away from meals, equivalent to 167 gm of fresh kale which is approximately 5 servings of vegetables, lowered LDL cholesterol and increased HDL cholesterol, serum selenium and glutathione peroxidase activity. [Biomed Environ Sci, 2008;21(2):91-7. 46391 (11/2008)] Summary Interview |
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HDL Cholesterol (elevating) - macadamia nuts - 40452 Macadamia nuts 40-90 gm/d (12-26 nuts or 40 gm = 1/3rd cup and 90 gm = 2/3rd cup). [J Nutr, 2003;133:1060-1063. 40452 (2003)] Summary Interview |
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HDL Cholesterol (elevating) - niacin (niaspan®) - 31515 Niacin (Niaspan®) intermediate-sustained release (eight to 12 hours) at bedtime: 375 mg in week one; 500 mg in week two; 750 mg in week three; and 1500 mg in week four. [Am J Cardiol, December 17, 1998; 82(12A): 24U-28U. 31515 (1999)] Summary Interview |
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HDL Cholesterol (elevating) - niacin - 40452 Niacin: Day 1 0.25 gm after lunch, 0.5 gm after dinner and 0.5 gm at night. Day 2 0.25 gm after breakfast, 0.5 gm after lunch, 0.5 gm after dinner and 1gm at night. Day 3 0.25 gm after breakfast, 0.5 gm after lunch, 1gm after dinner and 1gm at night. Day 4 1 gm q.i.d., taken immediately after meals and at bedtime. Niacin therapy: Fibrinogen is lowered by 15%; raises HDL-C by 20- 40%; HDL2-C, the large HDL particle is raised by up to 100%; a negligible effect on smaller HDL3; LDL-C is lowered by 15-30%;small, dense LDL particles are significantly lowered; triglycerides are lowered by 15-40%; and Lp(a) decreases10-40%. [J Intern Med. 2005 Aug;258(2):94-114. 43553 (01/2005)] Summary Interview |
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HDL Cholesterol (elevating) - pistachio nuts - 32246B/32246 Pistachio nuts (monounsaturated fatty acids (MUFA) comprise 67 percent of total fat in pistachios; high in vitamin E and fiber) substituting 20 percent of the daily caloric intake instead of high saturated fat foods reduced total cholesterol and increased HDL cholesterol. [J Am Coll Nutr, 1999;18(3):229-232. 32246B/32246 (1999)] Summary Interview |
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HDL Cholesterol (elevating) - red yeast rice - 47484 Red yeast rice in 300 mg capsules, 2 capsules two times daily away from meals. [Asia Pac J Clin Nutr, 2009;18(3):310-7. 47484 (12/2009)] Summary Interview PubMed |
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HDL Cholesterol (elevating) - royal Jelly - 23823 Royal Jelly (67% water, 12% protein, 12% carbohydrate, 5% fat, 1% minerals and about 2% other substances, i.e. vitamins, nucleic acids and other not yet analyzed chemical compounds) 50-100 mg/d orally or 10-100 mg by injection. [Experientia, 1995; 51:927-935. 23823 (1995)] Summary Interview |
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HDL Cholesterol (elevating) - sesame oil - 48437 Sesame oil 35 grams per day with a fatty acid breakdown of 15.23g of linoleic acid (omega-6)/35g of oil and 14.42g of oleic acid (MUFA)/35g of oil. [Clin Nutr, 2010 Dec 15; [Epub ahead of print]. 48437 (4/2011)] Summary Interview PubMed |
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HDL Cholesterol (elevating) - soy protein - 42786 Soy protein containing 80 mg/d isoflavones (foods containing approximately 40 mg of isoflavones include 2 cups of soy milk, 120 g of uncooked tofu, 20g of soy flour or soy protein isolate, 75 g of uncooked tempeh, half cup of uncooked green soybeans, or 20 g of roasted or mature soybeans). [Am J Clin Nutr, 2005;81;397-408. 42786 (04/2005)] Summary Interview |
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HDL Cholesterol (elevating) - vitamin c - 20548 Vitamin C in plasma directly related to HDL cholesterol. Vitamin C from diet 150-250 mg may increase HDL levels. [Am J Clin Nutr, 1994;60:100-105. 20548 (1995)] Summary Interview |
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HDL Cholesterol (elevating) - vitamin c - 20548 Vitamin C 500 mg/d or more. [Journal of Chiropractic Medicine, 2008; 7(2): 48-58. 46339 (061108)] ltt Summary |
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HDL Cholesterol (elevating) - vitamin e - 35165 Vitamin E 200 mg/d - 400 mg/d (D,L-α-tocopherol) reduced HDL and LDL oxidation but increased small atherogenic LDL particles. [Atherosclerosis, 2000;150:129-134. 35165 (2000)] Summary Interview |
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Headache (sleep disorder) - Melatonin Melatonin may help headaches related to sleep disorders. [Developmental Medicine Child Neurology, 2004;46:776-782. 42513 (02/2005)] Summary Interview |
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Hearing Loss (Presbycusis) - antioxidant - 35497 Antioxidants (CoQ10, alpha lipoic acid, acetyl-L-carnitine, glutathione) and diet restriction may benefit age-related hearing loss. [Laryngoscope, May, 2000;110:727-738. 35497 (2001)] Summary Interview PubMed |
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Hearing Loss (Presbycusis) - antioxidants - 35497 Antioxidants (CoQ10, alpha lipoic acid, acetyl-L-carnitine, glutathione) and diet restriction may benefit age-related hearing loss. [Laryngoscope, May, 2000;110:727-738. 35497] Summary Interview PubMed |
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Hearing Loss (Presbycusis) - bed rest, prednisone, magnesium, vitamin e - 41055 Bed rest, prednisone 1 mg/kg/d, carbogen (95% oxygen plus 5% carbon dioxide by mask) for 30 minutes, 4 times a day and magnesium 4 gm/d I.V. and vitamin E 400 mg P.O. b.i.d. (Sudden Idiopathic Hearing Loss: SIHL). [Otology Neurotology, 2003;24:572-575. 41055 (2004)] Summary Interview PubMed |
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Hearing Loss (Presbycusis) - coenzyme q10 - 43467 Coenzyme Q10 75 mg b.i.d. (mitochondrial 7445A→G mutation). [Acta Oto-Laryngologica, 2005;125:510-512. 43467 (8/2005)] Summary Interview PubMed |
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Hearing Loss (Presbycusis) - coenzyme q10 - 47990 Coenzyme Q10 160 mg q.d. (Q-TER®) with food. [Acta Otolaryngol. 2010 May 5; [Epub ahead of print]. 47990 (7/2010)] Summary Interview PubMed |
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