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Expert Pearls

Abdominal Pain

Abruptio Placenta

Acne

Addiction

Adenomatous Polyps

Adrenoleukodystrophy (ALD)

Adult Respiratory Diistress Syndrome (ARDS)

Age Related Macular Degeneration

Aggression

Aging

AIDS/HIV

Akathisia (Neuroleptic-Induced)

Alcoholism

Allergic Rhinitus

Allergies

Alzheimer’s Disease

Amenorrhea

Amyotrophic Lateral Sclerosis (ALS)

Anaphylaxis (Exercise-Induced)

Anemia (megaloblastic)

Anger (substance abuse)

Angina Pectoris

Anklyosing Spondylitis

Ann Allergy

Anticoagulation Therapy

Antioxidants

Anxiety (substance abusers)

Arrhythmias

Arthritis (polyarthritis)

Asthma

Atherosclerosis

Atopic Dermatitis / Eczema

Atrial Fibrillation

Atrophic Vaginitis

Attention-Deficit /Hyperactivity Disorder

Autism

Autoimmune Disease

Back Pain

Behavior (violent)

Behavior Disorder

Behcet’s Disease

Benign Prostatic Hypertrophy (BPH)

Blepharitis

Bone Loss

Breast Feeding

Bronchiectasis

Burns

C-Reactive Protein (lowering)

Cancer

Candidiasis (oral)

Cardiac Function

Cardiomyopathy (idiopathic)

Cardiovascular Disease

Cardiovascular Surgery

Carotid Atherosclerosis

Catabolic State

Cataract

Celiac Disease

Cellulite

Cerebral Atrophy

Cerebral Hypofusion

Cerebral Palsy

Cerebral Vascular Disease

Chemoprevention

Cholesterol Lowering

Chromium

Chronic Disease

Chronic Obstructive Pulmonary Disease (COPD)

Cirrhosis

Clostridium Dificille (diarrhea)

Cognition

Colic (infantile)

Common Cold

Complex Regional Pain Syndrome (CRPS)

Constipation

Contraception

Coronary Artery/Heart Disease (see also cardiovascular disease)

Cough

Cough (URI)

Cow’s Milk

Critical Illness

Crohn’s Disease

Cystic Fibrosis

Deafness

Dementia

Dental Caries

Depression

Diabetes Mellitus

Diabetic Neuropathy

Diarrhea

Diet (general)

Docosahexaenoic Acid (DHA)

Down Syndrome

Dry Eye Syndrome

Dysfunctional Gut Syndrome

Dyslexia

Dysmenorrhea

Dyspepsia

Dysplasia (cervical)

Ear Infection

Eczema

Encephalopathy

Endothelial Function

Enteritis (radiation-induced)

Enuresis (nocturnal)

Epilepsy

Epitaxis

Erectile Dysfunction

Erythema Nodosum

Erythroderma

Estrogen Metabolism

Exercise

Exercise (duodenal ulcer)

Falling

Fatigue

Fibrinogen (lowering)

Fibrocystic Breast Disease

Fibroids (uterine)

Fibromyalgia

Fibrosis

Folic Acid

Fracture

Fracture (hip)

Fragile X Syndrome (FXS)

Gastroesophageal Reflux Disease (GERD)

Gestational Diabetes

Gingivitis (see also periodontal disease)

Gout

Grave’s Disease

Grave’s Ophthalmopathy

Growth and Development

Halitosis

HDL Cholesterol (elevating)

Headache

Headache (sleep disorder)

Hearing Loss (Presbycusis)

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Heart Rate Variability (HRV)

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Immune Function

Infection

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Inflammatory Bowel Disease

Insomnia

Insulin Resistance/Hyperinsulinemia

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Intestinal Permeability

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Ischemic Heart Disease

Kidney Stone

Kidney Transplantation

Lactation (see breast-feeding)

Lactic Acidosis

Lactose Intolerance

Lead Excess/Poisoning

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Leukemia - Myelogenous

Libido

Lipoprotein (a) (lowering)

Liver Disease

MATHS

Meibomian Gland Dysfunction

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Melatonin

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Metabolic Syndrome

Microalbuminuria

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Mind-Body

Miscarriage

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Motion Sickness

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Muscle Pain

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Muscle Wasting

Muscular Dystrophy

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Myopathy (skeletal)

Myositis

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Necrotizing Enterocolitis (NEC)

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Niacin Therapy

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Obstructive Sleep Apnea Syndrome

Osteoarthritis

Osteoporosis

Otitis Media

Pain (musculoskeletal)

Pain (Neuropathic)

Pancreatitis

Panic Disorder

Parkinson's Disease

Pemphigus (bullous)

Periodontitis /Periodontal Disease

Peripheral Vascular Disease

Pernicious Anemia

Pet Therapy

Phenylketonuria

Physical Performance

Phytoestrogens

Pityriasis Rubra Pilaris

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Pneumonia

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Polycystic Ovarian Syndrome

Portal Hypertension

Pre-Eclampsia

Pregnancy

Premature Delivery

Premature Graying

Premature Infant

Premature Rupture of Fetal Membranes (PROM)

Premenstrual Syndrome

Probiotics

Psoriasis

Rabies

Radiation Exposure

Renal

Restless Leg Syndrome

Retinitis Pigmentosa

Retinopathy

Rheumatic Disease

Rheumatic Disease

Rheumatoid Arthritis

Rhinitis (allergic)

Salicylate Intolerance

Sarcoidosis

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Satiety

Schizophrenia

Seasonal Affective Disorder (SAD)

Seizures

Selenium

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Serous Otitis Media (see otitis media)

Sexual Activity/Behavior

Shock (septic shock)

Sickle Cell Anemia

Silicone Breast Implant Syndrome

Sleep Disorder

Smoking

Soy Foods

Stress

Stroke

Substance Abuse

Sudden Infant Death Syndrome

Suicide

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Syndrome X

Systemic Lupus Erythematosus (SLE)

Testosterone Replacement Therapy

Thalassemia

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Thyroiditis

Tinnitus

Trans Fatty acids

Transplantation (renal)

Trauma

Triglycerides (lowering)

Tuberculosis (Mycobacteria)

Ulcer (duodenal)

Ulcer (gastric - helicobacter pylori)

Ulcer (pressure)

Ulcerative Colitis

Upper Respiratory Infection (URI)

Uric Acid

Urinary Tract Infection

Urticaria (chronic)

Uveitis

Vaginitis

Vegan / Vegetarian Diet

Ventricular Function

Very Low Birth Weight Infants

Veterinary Medicine

Violence

Vision

Vitamins

Vitiligo

Warts

Warts (genital)

Weight Gain

Wilson Disease

 

Diet (general) - Crops /Fertilizers

Nutritional content of crops from conventional fertilizers have imbalances in nutritional content and can have excess of toxic metals. [J Altern Complemen Med, 2001;7(2):161-173. 37809 (2001)] Summary Interview

Diet (general) - Crops /Herbicides

Nutritional content of crops from conventional herbicides can have lower protein content. [J Altern Complemen Med, 2001;7(2):161-173. 37809 (2001)] Summary Interview

Diet (general) - fruits and vegetables

Nutritional content of fruits and vegetables has declined over the last 60 years. [J Altern Complemen Med, 2001;7(2):161-173. 37809 (2001)] Summary Interview

Diet (general) - Mediterranean diet

Diet (general) - Mediterranean diet - 2 phenolic/antioxidant compounds; monunsaturated fatty acids replace saturated fat, protect LDL cholesterol from oxidation; moderate dairy product consumption; rich in fruits and vegetables; whole grain bread; reduced in trans fatty acids; low in meat, and dairy products; fruit for dessert except for special occasions. [Am J Clin Nutr, 1995;61(suppl):1402S-6S. 22553 (1996)] Summary Interview

Diet (general) - Mediterranean diet - 2

Mediterranean diet lowers LDL while not effecting HDL cholesterol; olive oil is a monunsaturated fatty acid rich in phenolic/antioxidant compounds; monunsaturated fatty acids replace saturated fat, protect LDL cholesterol from oxidation; moderate dairy product consumption; rich in fruits and vegetables; whole grain bread; reduced in trans fatty acids; low in meat, and dairy products; fruit for dessert except for special occasions. [Am J Clin Nutr, 1995; 61(Suppl.):1321S-3S. 22547 (1995)] Summary Interview

Diet (general) - Organic crops

Organic crops had on average up to 30% more vitamin C, iron, magnesium and phosphorus and significantly less nitrates. [J Altern Complemen Med, 2001;7(2):161-173. 37809 (2001)] Summary Interview

Diet (general) - Organic farming

Organic farming benefits include cleaner water; an absence of pesticide residues; preserves wildlife habitat and wildlife is not poisoned; organic composts can breakdown pesticides and other toxic chemicals thereby cleaning the environment; and safeguarding and replenishing topsoil. [J Altern Complemen Med, 2001;7(2):161-173. 37809 (2001)] Summary Interview

Diet (general) - Organic grown protein

Organic grown protein is of lower quantity but better quality for human nutrition due to the reduction in nitrogen use. [J Altern Complemen Med, 2001;7(2):161-173. 37809 (2001)] Summary Interview

Diet (general) - Pediatric nutrition

Pediatric nutrition - average child in U.S. views more than 25 hours of television per week; approximately 3 hrs/wk of food advertisements; 43.6% in "fats, oils and sweets" food group, 37.5% in "bread, cereal, rice and pasta group (23% of these were for high-sugar breakfast cereals); 11% for fast-food restaurants. [J Am Diet Assoc, April 14, 1994;94:1296-1300. 21597 (1995)] Summary Interview

Diet (general) - Pediatric nutrition - 2

Pediatric nutrition - children watch on television 21.3 commercials per hour; 47.6% were food related; 91% of commercials were high in fat, salt or sugar; children 3 to 5 years of age watch on average 21.4 hours per week; #1 category of advertised foods were cereals, #2 were candies and other snack foods;15% of food-related commercials were for restaurants - mostly fast-food; of cereals advertised 85% were high in sugar; of the advertised beverages, a minority were carbonated (5.6%); 83.2% were beverages that were sweetened. [Arch Pediatr Adolescent Med, June, 1995;149:649-652. 22563 (1996)] Summary Interview

Diet (general) - Pediatric nutrition - 3

Pediatric nutrition - half of all the television ads that children view are for food, especially sugar–rich cereal and high-caloric snacks; on Saturday morning television 61% of the commercials are for food, and more than 90% of those are for sugared-cereals, candy bars, fast-foods, chips, and other nutritionally unsound foods; one-quarter of all preschoolers, one-half of all older children, and two-thirds of all teenagers have a television set in their own bedroom. [Develop Behav Pediatr, June 2001;22(3):185-187. 38178 (2001)] Summary Interview

Diet (general) - Primate diet vs. Western diet

Nutritional content of versus Western diet - more leafy vegetables, wild fruit, fiber, alpha-linolenic acid, vitamin C, plant protein, less high calorie-carbohydrate/sugar rich food. [Nutrition 1999;15(6):488-498. 33148 (2000)] Summary Interview

Diet (general) - Vegan

Vegan diets, and to a lesser extent lacto-ovovegetarian diets, have reduced toxin and heavy metal exposure than animal food-based diets. [Am J Clin Nutr, 2004;80:237-238. 41817 (2004)] Summary Interview

Docosahexaenoic Acid - Functions

Functions - anti-inflammatory by converting to EPA; converts moderately to EPA; flaxseed oils ALA can convert somewhat to DHA; heart attack mortality reduced; plant source from microalgae; memory function; neurodevelopement of fetus/infant; triglyceride lowering. [Pharmacol Res 1999;49(3):211-225. 33885 (2000)] Summary Interview

Down Syndrome - Folate metabolism

Folate metabolism disorder in mother. [Eur J Obstet Gynecol Reprod Biol, 2006 Feb 1;124(2):130-3. Epub 2005 Oct 5. 44196/44621 (4/2006)] http://www.vitasearch.com/get-clp-summary/35220 Summary

Down Syndrome - Folic acid /B12

Folic acid and/or B12 supplementation to normalize altered “One Carbon Metabolism “ important for methylation; DNA/RNA nucleotide synthesis. [Eur J Obstet Gynecol Reprod Biol, 2006 Feb 1;124(2):130-3. Epub 2005 Oct 5. 44196/44621 (4/2006)] Summary Interview

Dry Eye Syndrome - sea buckthorn oil - 48071

Sea buckthorn oil in 500 mg capsules at 2 grams per day in divided doses with meals. [J Nutr, June 16, 2010; [Epub ahead of print]. 48071 (8/2010)] Summary Interview PubMed

Dysfunctional Gut Syndrome - Diet

Diet low in fermentable, starchy and yeasty foods; diet high in unrefined starches and vegetables - small amounts of fruit; higher in fats and protein; supplement with B vitamins, magnesium, gamma-linolenic acid; reduce or eliminate the consumption of refined sugars and a high intake of lectins. [J Royal Soc Med, 1995;88:63-66. 22682 (1995)] Summary Interview

Dysfunctional Gut Syndrome - Gut fermentation

Abnormal gut fermentation frequently presents with symptoms of irritable bowel, catarrhal symptoms and mild cerebral dysfunction such as inability to concentrate, fatigue and "brain fog or fag.” The best test is excess ethanol production on a fasting sugar challenge (normal < 22 micromoles per liter). Excess β-alanine excretion is another test. [J Royal Soc Med, 1995;88:63-66. 22682 (1995)] Summary Interview

Dyslexia - Fatty acid

Fatty acid (PUFA) - high-DHA (docosahexaenoic acid) fish oil and evening primrose oil (daily dose: 480 mg DHA, 108 mg EPA, 96 mg GLA, and 35 mg AA) given in two divided doses with meals. [J Med Food, 2007;10(4): 662-6. 46027 (5/2008)] Summary Interview

Dysmenorrhea - Eicosapentaenoic acid

Eicosapentaenoic acid (EPA) 1 gm and docosapentaenoic acid (DPA) 0.72 gm per day in 2 divided doses. [Am J Obstet Gynecol, April, 1996;174: 1335-8. 24741 (1996)] Summary Interview

Dysmenorrhea - Pycnogenol®

Pycnogenol® 30 mg b.i.d. after morning and evening meals. [J Reprod Med, 2008; 53(5): 338-46. 46418 (8/2008)] Summary Interview

Dyspepsia - Artichoke leaf extract

Artichoke leaf extract (ALE) 320 mg 6/d (1920 mg of total standardized extract). [J Altern Complem Med, 2004;10(4):667-669. 42219 (12/2004)] Summary Interview

Dysplasia (cervical) - Antioxidants

Antioxidants in the diet reduced. [Am J Repro Immunol, 1994;32:221-225. 21510 (1996)] Summary Interview

Ear infection - Elimination diet

Food elimination diet of cows milk, wheat, egg white, peanut, soy, orange, tomato, chicken and apple. [Ann Allergy, September 1994;73:215-219. 20995 (1996)] Summary Interview

Ear Infection - Food allergy

Food allergy a cause of. [Ann Allergy, September 1994;73:215-219. 20995 (1996)] Summary Interview

Encephalopathy - Acetyl-L-carnitine

Acetyl-L-carnitine (ALC) 2gm b.i.d..(hepatic encephalopathy] [Dig Dis Sci, 2008 Mar 21; [Epub ahead of print]. 46359 (06-15-08)] ltt Summary

Encephalopathy - Antioxidant

Antioxidant mixture by mouth including CoQ10, NADH, vitamin E, alpha-lipoic acid, a multivitamin in a fresh fruit and vegetable puree (in hospital by family, case report); subsequent gastric feeding tube administration (rehabilitation hospital) of CoQ10, alpha-lipoic acid, NADH, vitamin C, vitamin E, B complex, multivitamin-mineral mixture, L-glutamine, omega 3 fatty acids, magnesium and a pureed mixture of fruits and vegetables concurrent with parenteral glutathione and ascorbate. (spongiform encephalitis/Creutzfeldt-Jakob disease). [J Am Coll Nutr, 2002;21(1):22-25. 38833 (2002)] Summary Interview

Encephalopathy - Coenzyme Q10

Coenzyme Q10 30 mg/kg/day in three divided doses (pediatric, genetic defect, coenzyme Q10 deficiency). [Neurology, 2005 Aug 23;65(4):606-8. 43616/43808 (11/2005)] Summary Interview

Endothelial Function - arginine - 32138

Arginine (L-) 5-8 gm/d is minimum effective dose; 18-20 gm/d is a maximum effective dose without significant side effects. [Cardiology 1999;90:153-159. 32138 (1999)] Summary Interview

Endothelial Function - calcium - 36718 / 39257

Calcium 1000 mg/d plus 2 mg estriol increased BMD and improved endothelial function. [J Am Geriatri Soc, April 2002;50(4):777-778. 36718 / 39257 (2002)] Summary

Endothelial Function - citrulline - 48344

L-citrulline with water at 2.4 grams in the morning before breakfast and 3.2 grams in the evening before sleeping. [Int J Cardiol, 2010, Nov 8; [Epub ahead of print]. 48344 (1/2011)] Summary Interview PubMed

Endothelial Function - coenzyme q10 - 45545

Coenzyme Q10 100 mg t.i.d. with meals improved endothelial function and extracellular SOD. [Eur Heart J, 2007 Jul 19; [Epub ahead of print]. 45545 (9/2007)] Summary Interview

Endothelial Function - diet - 28669

Diet - high fat meal increases endothelial dysfunction. [JAMA, November 26, 1997;278(20):1682-1686. 28669 (1998)] Summary Interview

Endothelial Function - diet / trans fatty acids - 42103

Diet rich in trans fatty acids (margarine, commercially baked products, and deep-fried fast food) impairs endothelial function. [Am J Clin Nutr, 2004;80:1029-1035. 42103 (11/2004)] Summary Interview

Endothelial Function - folic acid - 22602 / 22112

Folic acid 5 mg/d and vitamin B6 250 mg/d. [Eur J Clin Investigation, 1995;25:176-181. 22602/22112 (1996)] Summary Interview

Endothelial Function - green tea catechins - 47757

Green tea catechins 80 to 580 mg/day once daily with meals. [Circ J, 2010 Feb 4; [Epub ahead of print]. 47757 (3/2010)] Summary Interview PubMed

Endothelial Function - isoflavone - 46714

Isoflavone 80 mg/day in a single dose with or without food. [Eur Heart J, 2008 Sept 23; [Epub ahead of print]. 46714 (12/2008) Summary

Endothelial Function - magnesium - 48178

Magnesium pidolate, a bioavailable organic salt, given by mouth at a dose of 4.5 grams per day providing 368 milligrams of elemental magnesium in two divided doses (morning and evening), with or without meals improve endothelial function. [Magnes Res, 2010 Aug 24; [Epub ahead of print]. 48178 (10/2010)] Summary Interview PubMed

Endothelial Function - omega-3 fatty acids - 46407

Omega-3 fatty acids (2 g/d DHA and 3 g/d EPA, fish oil) in 3 divided doses with meals increased stroke volume and cardiac output. [Eur J Appl Physiol, 2008 June 18; [Epub ahead of print]. 46407 (8/2008)] Summary Interview

Endothelial Function - tea (black) - 45109

Tea (black) - the addition of milk negates the enhancement of nitric oxide and improvement in endothelial function that plain tea provides by milk caseins forming complexes with the protective tea catechins. [Eur Heart J, 2007; 28(2): 219-23. 45109 (6/2007)] Summary Interview

Endothelial Function - vitamin c - 28669

Vitamin C 1,000 mg/d and vitamin 800 IU/d after high fat meal. [JAMA, November 26, 1997;278(20):1682-1686. 28669 (1998)] Summary Interview

Endothelial Function - vitamin c - 29230 / 29224

Vitamin C 2 gm/d in heart failure patients. [Circulation, 1998;97:363-368. 29230/29224 (1998)] Summary Interview

Endothelial Function - vitamin c - 33832

Vitamin C .5-2gm/d. [Eur Heart J, 1999;1676-1680. 33832 (2000)] Summary Interview

Endothelial Function - vitamin c - 33832

Vitamin C 3 gm in an intravenous infusion of 100 ml 0.9% saline over 10 minutes. [Eur Heart J 1999;1676-1680. 33832 (2000)] Summary Interview

Endothelial Function - vitamins c - 40905

Vitamins C 500 mg/d and E 400 IU/d. [Circulation, 2003;108:1059-1063. 40905 (2003)] Summary Interview

Endothelial FunctionDiet - fruits / vegetables / fish - 42103

Diet rich in fruits (antioxidants), vegetables (folic acid), and fish (n-3 fatty acid) benefits endothelial function. [Am J Clin Nutr, 2004;80:1029-1035. 42103 (11/2004)] Summary Interview

Enteritis (radiation-induced) - Lactobacillus acidophilus

Lactobacillus acidophilus (NFCO) 1748 daily 1010 c.f.u. daily in 150 ml of yogurt starting 5 days prior to radiotherapy, daily during the therapy and for 10 days after completing radiotherapy. [Fifth International Meeting on Progress on Radio-Oncology, May 1995;10-14:501-504. 23402 (1995)] Summary Interview

Enuresis (nocturnal) - Acupuncture therapy

Acupuncture therapy (traditional Chinese). [Scand J Urol Nephrol, 2001;35:40-43. 37046 (2001)] Summary Interview

Epilepsy (see seizures) - Eicosapentaenoic Acid

Eicosapentaenoic Acid (EPA) 1 gm/d and docosahexaenoic acid (DHA) .7 gm/d (refractory seizures). [Epilepsy Behav. 2005 Sep;7(2):253-8. 43785 /44072 (1/2006)] Summary Interview

Epilepsy (see seizures) - Multivitamin /Mineral

Multivitamin/mineral, calcium, magnesium, selenium (glutathione peroxidase), zinc, folic acid, vitamins B6, B12, C, D, E and K. [J Pharmacol Sci 2005 Aug;98(4):340-53. Epub 2005 Aug 2. 44610 (5/2006)] Summary Interview

Epitaxis - n-acetylcysteine - 47360

N-acetylcysteine 600 mg t.i.d. with or without meals in patient with Hereditary Hemorrhagic Telangiectasias. [Rhinology, 2009 Mar;47(1):85-8. 47360 (12/2009)] Summary Interview PubMed

Erectile Dysfunction - acetyl-L-carnitine - 43770

Acetyl-L-carnitine 2 gm/d and proprionyl-l-carnitine 2 gms/d. [Urology, 2005;66(5):1080-5. 43770 (5/2006)] Summary Interview

Erectile Dysfunction - arginine - 44952

Arginine 1.7 g/d (dipeptide arginyl aspartate) and Pycnogenol® 80-120 mg/d. [Sex Marital Ther. 2003 May-Jun;29(3):207-13. 44952 (7/2006)] Summary Interview

Erectile Dysfunction - korean red ginseng - 45682

Korean Red Ginseng 1000 - 3000 mg/d before breakfast. [Asian J Androl, 2007; 9(2): 241-4. 45682 (11/2007)] Summary

Erectile Dysfunction - propionyl-l-carnitine - 45315

Carnitine - propionyl-l-carnitine (PLC) 1 gm b.i.d. independently from Sildenafil 50 mg b.i.w. and meals in diabetic patients with erectile dysfunction reduced oxidative stress and improved endothelial dysfunction markers in type 2 diabetic patients with erectile dysfunction and had more sustained improvement in symptoms of E.D. than Sildenafil alone. [Eur Urol, 2007 Apr 25; [Epub ahead of print]. 45315 (7/2007)] Summary Interview

Erectile Dysfunction - yohimbine - 26601 / 26602

Erectile DysfunctionYohimbine 5-10 mg t.i.d.. [Arch Sexual Behavior, 1997;26(1):49-62. 26601 / 26602 (1997)] Summary Interview

Erectile Dysfunction - yohimbine - 39233

Yohimbine 5.4 mg -10.8 mg t.i.d. or 5.4 mg 1-2 tablets 15-30 minutes before sex. [Intern J Impotence Res,2002;14:25-31. 39233 (2002)] Summary Interview

Erythema Nodosum - Vitamin B12

Vitamin B12 I.M. 1000 mcg twice a week x 4 weeks then monthly I.M. vitamin B12 1000 mcg. At six months oral sublingual vitamin B12 1000 mcg twice a week (case report of complete remission). [J Am Board Fam Pract. 2005 Nov-Dec;18(6):567-9. 43946/44357 (1/2006)] Summary Interview

Erythroderma - Folic acid

Folic acid 2.5 mg/d, vitamins B6 50 mg/d and vitamin B12 1 mg/d (in case of concurrent methotrexate therapy supplementation with 15 mg of calcium folinate the day after the administration of methotrexate). [ J Dermatolog Treat, 2007;18(3):138-46. 44991/45996 (11/2007)] Summary Interview

Estrogen Metabolism - Dioxin exposure

Dioxin exposure may decrease the 2:16 estrogen ratio by increasing16-hydroxyestrogens. [Arch Environ Occup Health, 2005 Jul-Aug;60(4):215-22. 45639 (03/2007)] Summary Interview

Exercise - antioxidants - 24460

Antioxidants (beta-carotene, vitamin C, vitamin E) can reduce oxidative damage in heavy exercisers. [Sports Medicine, 1996;21(3):213-238. 24460 (1996)] Summary Interview PubMed

Exercise - antioxidants - 34758

Antioxidants - beta-carotene 32 mg/d, vitamin C 1000 mg/d, vitamin E 600 mg/d reduced lipid peroxides and prevented reductions in vitamin C levels in professional basketball players. [Int J Sports Med, 2000;21(2):146-150 . 34758 (2000)] Summary Interview PubMed

Exercise - athletes, probiotics - 48851

Lactobacillus rhamnosus and Lactobacillus paracase at 109 cells per day in a powder suspended in water (aqueous suspension) in the morning, during breakfast in a single dose. [ Curr Microbiol, 2011 June; 62(6):1689-96. 48851 (11/2011)] Summary Interview PubMed

Exercise - beetroot juice - 47417

Beetroot juice (nitrate rich) 500 ml sipped throughout the day. [J Appl Physiol, August 6, 2009; [Epub ahead of print]. 47417 (10/2009)] Summary Interview PubMed

Exercise - branch chain amino acids (bcca) - 45547

Branch chain amino acids (BCAA) 6 gms/d in 5 divided doses during the run, an additional 2 grams administrated on the day of 25-km run (2g/500ml; 0.4% mixture of BCAA in a 4% carbohydrate solution) reduced muscle soreness, fatigue and LDH elevation. [J Sports Med Phys Fitness, 2007; 47(3): 316-322. 45547 (12/2007)] Summary Interview PubMed

Exercise - caffeine - 20801

Caffeine 3 mg of caffeine per kilo of body weight (approximately1 to 1½ mugs of strong coffee) as ergogenic aid for endurance and sprint activity. [J Applied Physiol, 1994;19(1):111-138. 20801 (1995)] Summary Interview

Exercise - carnitine - 25588

Carnitine (-L) 3 gm/d reduced DOMS (delayed onset muscle soreness) and CPK levels after eccentric exercise of the quadriceps (20 minute single step test). [Int J Sports Med, 1996;17:320-324. 25588 (1997)] Summary Interview

Exercise - citrulline mallate - 47908

Citrulline malate 8 grams one hour before the training session. [J Strength Cond Res, 2010 Apr 7; [Epub ahead of print]. 47908 (6/2010)] Summary Interview PubMed

Exercise - coenzyme q10 - 46214

Coenzyme Q10 100mg b.i.d. (1 tablet, “fast-melt”) taken 30 minutes prior to each meal (morning and night). [J Int Sic Sports Nutr, 2008; 5(1): 8. 46214 (7/2008)] Summary

Exercise - coenzyme q10 - 47366

Coenzyme Q10 100 mg daily in a single dose every 24 hours in powder-filled capsules in the morning after breakfast increased anaerobic capacity. [J Strength Cond Res, 2009 July 28; [Epub ahead of print]. 47366 (10/2009)] Summary Interview PubMed

Exercise - coenzyme q10 - 48741

Coenzyme Q10 100 mg daily in a single dose (powder-filled capsules) in the morning after breakfast for 8 weeks decreased malondialdehyde (oxidative stress) after repeated short-term supramaximal exercise. [ J Sports Med Phys Fitness, 2011 June;51(2):305-12. 48741 (8/2011)] Summary Interview PubMed

Exercise - creatine - 28249 / 28621 / 28250

Creatine 20 g/d loading dose x 5 days then 2-5 gm/d (‘sprinting’ type exercises). [Internat J Sports Med, 1997;18:369-372. 28249, 28621/28250 (1997)] Summary Interview

Exercise - creatine - 32700

Creatine 20 g/d loading dose x 5 days then 2-5 gm/d (‘sprinting’ type exercises). [Clin J Sports Med 1998;8(4):286-297. 32700 (1999)] Summary Interview

Exercise - creatine - 34329

Creatine 20 g/d loading dose x 5 days then 2-5 gm/d (‘sprinting’ type exercises). [J Sports Med Phys Fitness, 1999;39:189-196. 34329 (2000)] Summary Interview

Exercise - disease prevention - 24181B

Disease prevention - daily participation in the prescribed exercise program has highly beneficial effects on cardiovascular diseases, diabetes, arthritis, hyperlipidemia, depression, cancer and COPD: a) by increasing blood supply to all organs and tissues; b) by improving muscle/tendon/ ligament/strength, mobility and flexibility; c) by the release of endorphins (the feel good hormones); d) by increasing bone formation; and e) by stimulating creativity. Exercise restores/improves the function of all body tissues and organs. [The Physician and Sports Medicine, February, 1996;24(2):72-78. 24181B (1996)] Summary Interview

Exercise - duodenal ulcer - 35844

Duodenal ulcer risk was reduced risk by approximately 50% in males with moderate or higher amounts of leisure-time physical activity (active - those who walked or ran 10 miles or more a week; moderately active - those who walked or ran less than 10 miles a week or did another regular activity). [West J Med, August 2000;173:101-107. 35844 (2000)] Summary Interview

Exercise - ginger - 47991

Two grams of ground ginger (either “raw” or “heat-treated”) divided into 6 capsules was taken in a single dose orally with water away from meals. [J Pain, 2010 Apr 23; [Epub ahead of print]. 47991 (8/2010)] Summary Interview PubMed

Exercise - juice plus® - 44563

Juice Plus® 6 capsules/d (12,500 IU vitamin A activity (100% from beta-carotene), 276 mg vitamin C, 108 IU vitamin E, 780 mcg folate, and 80 mg calcium per day, in addition to other phytonutrients / reduced post-exercise protein carbonyls). [Med Sci Sports Exerc, 2006; 38(6): 1098-105. 44563 (12/2006)] Summary Interview

Exercise - lactobacillus paracase, lactobacillus rhamnosus - 48851

Lactobacillus rhamnosus and Lactobacillus paracase at 109 cells per day in a powder suspended in water (aqueous suspension) in the morning, during breakfast in a single dose. [Curr Microbiol, 2011 June; 62(6):1689-96. 48851 (11/2011)] Summary Interview PubMed

Exercise - magnesium orotate - 31201

Magnesium orotate 1,000 mg (65.6 mg of elemental magnesium) t.i.d. improved cardiovascular function and exercise tolerance in CHD patients. [Cardiovascular Drugs and Surgery, 1998;12:153-156. 31201 (1999)] Summary Interview

Exercise - melatonin - 48703

Melatonin in 3 mg capsules taken orally, 1 capsule two days before the exercise test with the dinner, 3 capsules on the previous day (breakfast, lunch and dinner), 1capsule one hour before beginning the physical test. [J Pineal Res, 2011 April 21; [Epub ahead of print]. 48703 (6/2011)] Summary Interview PubMed

Exercise - ribose - 40023

Ribose 5 g dissolved in water and ingested 30 - 60 minutes before and after weight-training regimen (total of 10 g/d). [Curr Therapeutic Res, August 2002;63(8):486-495. 40023 (2003)] Summary Interview

Exercise - vitamin c - 31868

Vitamin C 500 mg/d. [Internat J Vit Nutr Res, 1999;69(1):41-44. 31868 (1999)] Summary Interview

Exercise - vitamin c - 44563

Vitamin C 1000 mg/d and vitamin E 400 IU/d (reduced post-exercise protein carbonyls). [Med Sci Sports Exerc, 2006; 38(6): 1098-105. 44563 (12/2006)] Summary Interview

Exercise - vitamin c - 44563

Vitamin C 1000 mg/d, vitamin E 400 IU/d and selenium 90 ug/d (reduced post-exercise muscle soreness). [Med Sci Sports Exerc, 2006; 38(6):1098-105. 44563 (12/2006)] Summary Interview

Exercise - vitamin c - 44694 / 46287

Vitamin C 1000 mg t.i.d. (pretreatment reduced muscle soreness). [Int J Sport Nutr Exerc Metab, 2006 Jun;16(3):270-80. 44694/46287 (4/2007)] Summary Interview

Exercise - vitamin d2, vitamin d3 - 48786

Vitamin D2 or D3 at 50,000 IU given once or twice weekly with breakfast in vitamin D insufficient (<32 ng/ml) hypercholesterolemic subjects suffering from statin-induced myositis-myalgias resulted in resolution of these symptoms with normalization of vitamin D levels (goal 40-80 ng/ml). [Curr Med Res Opin, 2011 July 6; [Epub ahead of print]. 48786 (9/2011)] Summary Interview PubMed

Falling - Calcium

Calcium 1,000 mg/d (elemental from calcium carbonate) and vitamin D3 400 IU (10 ug) reduced risk. [Aging Clin Exp Res. 2005 Apr;17(2):125-32. 43407, 43537/43598 (9/2005)] Summary Interview

Falling - Calcium citrate

Calcium citrate 1000 mg/d (elemental ) in divided doses with meals and vitamin D2 1000 iu/d with the evening meal. [Arch Intern Med, 2008;168(1):103-8. 46001 (6/2008)] Summary Interview

Fatigue - Caffeine withdrawal

Caffeine withdrawal symptoms in a.m.. [The Lancet, 1997;349:279-281. 27049 (1997)] Summary Interview

Fatigue - Diet

Diet - eliminate caffeine, sucrose and eat a higher protein and lower carbohydrate diet x 2 weeks. [The Nutrition Report, March 1991;9(3):17,24. 12081 (1996)] Summary Interview

Fatigue - Vitamin B12

Vitamin B12 normal ranges should be 600 to 2000 pg/ml. Below 550 to 600 pg/ml deficiencies start to appear in the CSF. Humans are born with serum levels of about 2000 pg/ml, which decline gradually throughout life. [Medical Hypotheses, 1991;34:131-140. 28725 (1998)] Summary Interview

Fatigue - vitamin c, intravenous - 49041

Vitamin C as ascorbic acid alone at 10 grams given over 30 minutes in 100 cc of normal saline improved fatigue in fatigued office workers without side effects. Fatigue symptoms improved within 2 hours and lasted for a day. Vitamin C reduced oxidative stress and increased blood levels of vitamin C. No other nutrients were give with the vitamin C. [ Nutr J. 2012 Jan 20; 11(1):7. 49041 (3/2012)] Summary Interview PubMed

Fibrinogen (lowering) - Alcohol

Alcohol (moderate); cigarette smoking cessation (significantly reduces); exercise; garlic; omega-3 fatty acid rich diets; vegetarian diet; weight loss. [Arterio, Thromb, Vasc Biol, September, 1995;15(9):1263-1268. 24063 (1996)] Summary Interview

Fibrinogen (lowering) - Cardiovascular risk factor

Cardiovascular risk factor. [Arterio, Thromb, Vasc Biol, September, 1995;15(9): 1263-1268. 24063 (1996)] Summary Interview

Fibrinogen (lowering) - Niacin

Niacin: Day 1 0.25 gm after lunch, 0.5 gm after dinner and 0.5 gm at night. Day 2 0.25 gm after breakfast, 0.5 gm after lunch, 0.5 gm after dinner and 1gm at night. Day 3 0.25 gm after breakfast, 0.5 gm after lunch, 1gm after dinner and 1gm at night. Day 4 1gm four times daily, taken immediately after the meals and at bedtime. Niacin therapy: Fibrinogen is lowered by 15%; raises HDL-C by 20- 40%; HDL2-C, the large HDL particle is raised by up to 100%; a negligible effect on smaller HDL3; LDL-C is lowered by 15-30%; small, dense LDL particles are significantly lowered; triglycerides are lowered by 15-40%; and Lp(a) decreases10-40%. [J Intern Med. 2005 Aug;258(2):94-114. 43553 (01/2005)] Summary Interview

Fibrinogen (lowering) - omega-3 fatty acids, epa, dha - 48958

Omega-3 fatty acid (EPA and DHA) serum levels are inversely associated with fibrinogen levels. Two fish servings per week approximately 1 gram combined EPA and DHA per day. [Eur J Clin Nutr, 2011 Sep 7; [Epub ahead of print]. 48958 (12/2011)] Summary Interview PubMed

Fibrinogen - Pycnogenol™

Pycnogenol™ 50 mg per tablet taken twice a day, after breakfast and after dinner. [Redox Rep, 2008; 13(6): 271-6. 46883 (3/2009)] Summary Interview PubMed

Fibrocystic Breast Disease - omega-3 fatty acid - 46920

Omega-3 fatty acid eicosapentaenoic acid (EPA) elevated in RBC is protective. Am J Clin Nutr, 2009; 89(1): 265-76. 46920 (4/2009) Summary Interview PubMed
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