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KIRK HAMILTON: Hi, my name is Kirk Hamilton, your host of Staying Healthy Today. Our mission is simple: To provide you credible usable health information from interviews and our educational resources to help you Stay and Be Well in the busy modern world. Please take a few moments before or after listening to this interview to browse through the Prescription2000.com website, the home of Staying Healthy Today Radio, for our free educational services.
Today's show topic is "Nutritional and Metabolic Status of Children with Autism." Our guest today is Dr. James B. Adams, who earned his PhD in material science and engineering from the University of Wisconsin, Madison, in 1987. Currently Dr. Adams is professor at Arizona State University doing research in developing computational models of materials and applying those models to the study of the properties of materials. He is also conducting research on heavy metal toxicity and autism, and recently co-authored a paper entitled "Nutritional and Metabolic Status of Children with Autism versus Neurotypical Children and the Association with Autism Severity" in the journal Nutrition and Metabolism.
Welcome, Dr. Adams. Thank you so much for being on the show today.
DR. JAMES B. ADAMS: Thanks for inviting me.
KIRK HAMILTON: So tell me. How does an engineering professor get involved with autism?
DR. JAMES B. ADAMS: Well I have a daughter with autism and when she was diagnosed roughly 17 years ago I was very frustrated at the lack of information on the causes of autism and how to treat it. And so I began looking into that. And so now I've shifted most of my research focusing on the causes of autism and how to treat it.
KIRK HAMILTON: Maybe we can backtrack a little bit and go, you know, how did you discover that your child had autism 17 years ago?
DR. JAMES B. ADAMS: Well my daughter had been very slow developing. By age 2 she still had no language, but even worse she didn't understand what was said to her. She was very slow learning how to walk, and she had some developmental delays and she had some really just not very social, not very interested in interacting with other people. And so that made my wife and I very concerned. And we had her hearing checked, it wasn't a problem. Age two and-a-half she was given a diagnosis of autism which was very devastating to us.
KIRK HAMILTON: So there's some, I've been to a lot of the autism conferences and there's some parents who go along with "a normal child" then suddenly it happens. So this apparently was something from birth you noticed that was off, or not correct?
DR. JAMES B. ADAMS: Right. She had a normal birth but was just slow developing from that point on and so I remember at a few months of age I was concerned she wasn't even initiating crawling very much. There were a number of times I'd push her across the bed. It was a mild concern at that point. My wife was actually a pediatric nurse and she didn't suspect anything for many months, but again it was just a gradual process. She didn't learn to interact with other people very much, she didn't learn language, didn't even understand when we called her by name. She didn't understand that.
KIRK HAMILTON: So she didn't have, for example, ill health, a lot of chronic infections when she was very, very young, or the you know the vaccine concept of sudden change. So it was just there.
DR. JAMES B. ADAMS: Well, it's a good question because she was vaccinated at age two months, four months, six months, 12 months, etc. So she had a lot of vaccinations as do all children. One of the major abnormalities was she had a long series of ear infections and was on oral antibiotics for many months. So I'm very suspicious of that, and my wife and I remain very suspicious for her early vaccination exposure, but when she had a booster shot at several years of life, she clearly worsened at that point.
KIRK HAMILTON: Well, you're - I was kind of baiting you in a way. I know Dr. Shaw's work. Who has done a lot with organic acids and his original experience with fungal metabolites being elevated in organic acid testing and then the sequelae of that. And so that's why I asked the question, that many experiences that I've heard of autistic parents is children do have chronic infections. Ear infection is one of them, and there may be an alteration of either bacterial flora or something like that, that in conjunction with the vaccines, et cetera, et cetera, pushed the load on the child toxicity load and then they get into trouble and manifest symptoms.
DR. JAMES B. ADAMS: Now we published four studies showing that kids with autism on average had twice the amount of oral antibiotic usage as did typical kids and that will absolutely affect their gut flora. Also children on oral antibiotics lose almost all of their ability to excrete mercury. So they're very vulnerable to mercury exposure at that time.
KIRK HAMILTON: You're perfect for actually - I'm a believer, but you're saying actually what I've experienced and studied. So at that moment, how supportive was the medical community to you when the diagnosis of autism occurred in your child?
DR. JAMES B. ADAMS: They were certainly sympathetic, but that they said we don't know anything about the cause of it, they said that it was a lifelong incurable condition. It was only a matter of time until my daughter would be institutionalized and that we should go to the autism society to seek more information on autism and support. But basically they had no information to give us on how to help her at all. So it was a very disappointing experience with them.
KIRK HAMILTON: And can you tell us - or so then where did you turn? What did you do?
DR. JAMES B. ADAMS: We went so several other, a couple of other places to confirm the diagnosis. We did go to the meeting at the autism society. We began speaking with parents. Ultimately, we learned about one type of therapy, one-on-one behavioral therapy. At the time there was only one other family doing it 60 miles from our home and we were told by other families not to try it because it was an abusive therapy, but we went and visited that family. We thought it actually made a lot of sense and we began implementing it for our daughter. And we were amazed. The very first day we began that, she came to the table and sat in a chair very compliantly and from - and began to very slowly make progress. By age five and-a-half, she was still nonverbal. But she'd take us by the hand to the fridge and we would have to guess what she wanted and we would say drink and she would say "kuh" and then we'd eventually get it to "drink" and then "want drink" and then "I want drink", "I want drink please" and that took years to slowly patiently teach her language.
KIRK HAMILTON: So you're saying behavioral therapy helped, but the question is when did you begin to think there was a biochemical or a biological component?
DR. JAMES B. ADAMS: That was several years later. I forget the exact time. Probably when my daughter was about 8 or so. My wife went to a biomedical conference by the Autism Research Institute and learned about it. I was fairly skeptical at the time. But then as I began reading about it, and the very great importance of vitamins and minerals for example to basic health, I became very interested in it and that was what started me doing research in that area.
KIRK HAMILTON: And that was about what time, ballpark?
DR. JAMES B. ADAMS: That was about 10 or about 11 years ago.
KIRK HAMILTON: The incidence of autism, I've heard anywhere from 1 out of 150-ish. Can you give me the newest -
DR. JAMES B. ADAMS: The official numbers from the CDC are that autism in the U.S. occurs, is now about 1 in 110 children. Some studies have put as high as 1 in 90. So it's about 1 in 100.
KIRK HAMILTON: So when someone, a traditional person might say "well, we're just diagnosing it more because we're better at it," what is your response to that?
DR. JAMES B. ADAMS: That's partly true. There was a large study by the Mind Institute which is the largest autism center in the U.S. and in the world, and their study showed that yes, about a quarter of the increase in autism is due to better diagnosis and about three-quarters of the increase is real.
KIRK HAMILTON: Well, okay, so then common sense would ask the question, what other disease on the planet has just skyrocketed so quickly if there's not some environmental component?
DR. JAMES B. ADAMS: Yeah, well there's certainly a lot of other disorders that have grown as well, peanut allergies, diabetes, etc., but there's - what this tells us and the latest study on looking at twins, identical twins and fraternal twins shows that it's both genetic and environmental. And it's estimated that - they estimate in that study the genetic component is about 38% and the environmental component is the majority of it.
KIRK HAMILTON: We are talking to Dr. James B. Adams, a professor at Arizona State University, who wrote a very interesting article in Nutrition and Metabolism called "Nutritional and Metabolic Status of Children with Autism Versus Neurotypical Children and the Association with Autism Severity," and is also a father, a parent of an autistic child. So let's fast-forward a bit and what therapies is your daughter getting now? She's seven - you say she's 17?
DR. JAMES B. ADAMS: She's 19 years old now.
KIRK HAMILTON: 19.
DR. JAMES B. ADAMS: We've done a huge number of therapies with her. Some more successful than others. But I'd say that overall one-on-one behavioral therapy has helped her slowly learn, but also very much the nutritional and biomedical treatments we've done to improve her overall nutritional status, to decrease her exposure to toxic metals and remove them from her. We've done many treatments which I think each one of them has had a little benefit. It's hard to say which has been the most, but now at age 19, she's gone from being completely nonverbal at age 5, now she can talk in simple phrases, she can read and write at about a third to fourth grade level, so she's made a lot of improvements. She still has a long ways to go. But we're really pleased and most importantly she's a very happy child. Very, very few behavioral problems as opposed to when she was younger. You can image if you can't communicate to the world even that you're hungry, imagine how frustrating that would be. Imagine the behavioral problems that would cause.
KIRK HAMILTON: Well let's use this as an example to get some of the premises out then. So what kind of dietary changes have you made and collectively that, you know, a lot of the autistic parents make that seem to have the most improvement in autistic children?
DR. JAMES B. ADAMS: Well we've tried very hard to make sure she eats a healthy diet, meaning one rich in vegetables and fruits and protein and limit her carb intake, and I think that's helped. But she's very sensitive to food so she's been on a gluten-free, casein-free diet for many years and I think that's very important. When she has food that's not on that diet, then she will often have behavioral problems. And so keeping her on that type of diet seems to be very beneficial to her.
KIRK HAMILTON: Would you say that let's say refined sugars and refined carbohydrates would cause more problems than let's say brown rice, let's say, or is that doesn't matter?
DR. JAMES B. ADAMS: We certainly try to avoid refined sugars and we reduce her carb intake some. But there was an interesting study that just came out of Harvard Medical School showing that about 70% of the kids with autism who are severe enough to have - have severe enough GI problems to do an endoscopy, 70% of those kids have problems digesting carbohydrates and sugars. Especially milk sugar is the biggest problem for them, so it's very strong argument why most families should consider a milk-free diet for their child.
KIRK HAMILTON: Well then let's move from there to the gut and how you might assess the gut and what role the gut, you know - I mean in my business, I've been a practicing physician assistant 28 years in integrative medicine, so that's where I start from. But to a conventional physician it makes no sense to kind of look inside for a headache or whatever you want to call it, or even behavior. So what kind of things have you done to assess your daughter's gut and what kind of agents do you give to help with that situation?
DR. JAMES B. ADAMS: My daughter tended to have mild constipation through her early childhood. Given the extent of all of her other problems it was not one, an area that we focused very much on. But through changing her diet, now that problem is pretty much resolved through just nutritional supplements and dietary improvements so now she doesn't have significant GI problems. We just published a study a few months ago showing when we evaluated GI function of kids with autism. So GI severity and autism severity, and we were surprised to see an extremely high correlation that the kids who had major GI problems tended to have much more severe autism. A very strong correlation between the two.
KIRK HAMILTON: So does your daughter take - for example the two things that would pop into my mind to help with that issue would be any kind of digestive aid and/or probiotics?
DR. JAMES B. ADAMS: Yes. We've kept her on digestive enzymes for many years and we also give her probiotic as well. However, despite that, we just did a very detailed study of gut bacteria using a DNA based method. She was one of a number of children we assessed and her gut flora is still very abnormal. And so the problem with those probiotics is they only contain one or a few or maybe at most a dozen beneficial bacteria. But a normal human gut has about 500 types of bacteria in it. So we are just beginning to learn what's normal and I think we're - really have a lot to learn about how to create a beneficial probiotic.
KIRK HAMILTON: Well this brings up another - I mean this is similar to me and I actually think I know the lab you're talking about that does the DNA stool exams or component to it, in that these autistic children would be evaluated by the four or five companies that do these kinds of comprehensive stool exams in an integrative medicine practice, and would that occur in a traditional approach to autism? I guess, let's say at the Mind Institute, for that matter?
DR. JAMES B. ADAMS: Well, I won't pick on the Mind Institute, but I will say I've spoken with a lot of traditional physicians and the general approach to doing lab measurements is maybe they'll search for genetic tests and maybe in a good day they'll check for iron status because that can be a problem for young children. And other than that, they generally won't do any medical tests and it's exceptionally hard for kids with even severe GI problems to get seen by a gastroenterologist. It's a huge problem for kids with autism. They're heavily discriminated against because of their mental challenges. There's some willful ignoring of their GI problems.
KIRK HAMILTON: But would the traditional gastroenterologist even look at this kind of approach with a comprehensive kind of stools that you do?
DR. JAMES B. ADAMS: Yes, some will. We've - there's one in particular, Tim Buie, who I think is one of the best gastroenterologists in the country for children with autism. And they are doing stool analyses and also it was his group that did the digestive enzyme measurements. There's other groups that have done those, too, but that's about the only place in the country that is really beginning to look at that. The problem with traditional stool analyses is that they're culture based, they can only culture 10 or 20 of the organism of the 500 in your gut, so you're seeing a tiny, tiny fraction of what's really there and they can - will miss many bacteria.
KIRK HAMILTON: Well let's move from there though - and this is in the controversial areas of, let's talk about heavy metals. You know, a theory is that mercury in the Thimerosal, you know, maybe push the envelope in kids that didn't detoxify well, especially in the situation if they had an infection and bad bacteria in their gut. So what do you think about just toxic metals in general, and then where might they come from if you think they're a problem?
DR. JAMES B. ADAMS: I've taught a course at ASU a couple of times on heavy metal toxicity. The thing to begin with is to realize how extremely common they are. My generation, the average adult lost 4 to 7 IQ points because of lead poisoning. So lead poisoning was very widespread in my generation and it's still a problem today, although not nearly as bad. Mercury poisoning, according to the FDA, 1 in 6 women in the U.S. has excessive levels of mercury that increase the risk of neurological damage in their child. There have been 40-some studies looking at toxic metal levels in kids with autism. Our group has been involved in a number of those and in most of these studies show that children with autism had increased levels of toxic metals. For example, in a baby teeth study we did, we found that children with autism have twice as much mercury in their baby teeth compared to typical children. And I was quite shocked to see that my daughter had actually one of the highest levels of anyone we tested.
KIRK HAMILTON: Now is this - this is with not having amalgams put in mercury or -
DR. JAMES B. ADAMS: Right. This is just pre-amalgams. So none of these children had any amalgam fillings and we were simply assessing using the teeth, the baby teeth because they form during - in utero and during the first few years of life. They're basically a measure of the cumulative exposure to toxic metals. So that previous study showing their great biomarkers for lead exposure, we used them to assess both lead and mercury exposure.
KIRK HAMILTON: Well let's talk about then the other sources. Where do you think some of this stuff comes from?
DR. JAMES B. ADAMS: Well there's three major sources of mercury. One is childhood vaccines. It's been removed from most but not all of them. For example, it's still in the flu vaccine given to infants and pregnant mothers which I think is tragic. It's also, mercury is present in many so-called silver dental fillings. So-called silver dental fillings are 35% silver, but 50% mercury, so they should be called mercury fillings. And they're so extremely toxic that the insert from the manufacturer tells the dentist to dispose of the leftover amalgam material in a toxic waste container. In other words, the only legal place you can put an amalgam filling is in a toxic waste container or strangely in someone's mouth. And that worries me.
KIRK HAMILTON: Well said.
DR. JAMES B. ADAMS: And then the third major source is from seafood. Very large fish at the top of the food chain like shark and swordfish have so much mercury in them that the FDA warns pregnant on their website that one serving of shark, one serving of swordfish during their entire pregnancy significantly increases the risk of brain damage to their child.
KIRK HAMILTON: This brings up the question, so how do you assess a young child? I know in our clinic, we will do calcium EDTA challenges and look for mercury that way with either DMSA or DMPS. How do you do it in a child and then how do you get rid of it?
DR. JAMES B. ADAMS: I think doing a chelation challenge with calcium EDTA is one great way, although EDTA tends to apply more to lead than to mercury. We published a study, actually a couple of studies, showing that chelation challenges result in much higher excretion of toxic metals and that in one study compared to typical kids, the kids with autism excreted about three times as much mercury as a typical kid when given a chelator. So I think that chelation challenges make a lot of sense because if you look at what comes out in the urine, and if there's a high amount of toxic metals coming out in the urine, it tells you two things. It tells you that it was in the body to begin with, and that the chelator is working and getting it out of the body. But there's also a porphyrin test which is a urinary test to look at abnormal porphyrins. Basically if the porphyrin pathway was abnormal, certain toxic metals like lead and mercury can inhibit that. So it's an indirect less invasive, slightly less invasive test.
KIRK HAMILTON: So you're painting the picture that there's probably more toxic metals in autistic children. Now then the question would be do they have reduced detoxification capabilities compared to the typical child so that it makes it a double whammy, so to speak? They have more, and then they can't get rid of them effectively?
DR. JAMES B. ADAMS: I think it's not like the case of lead poisoning where kids became lead toxic because of eating lead paint. Rather, we think it's mostly due to a decreased detoxification ability. There have been several published studies including a couple by our group showing kids with autism have less glutathione, and glutathione is the primary defense against toxic metals. And so they have less of it, and what they have tends to be more oxidized or inactive. So I think that's part of the reason why they're more vulnerable to toxic exposure and they cannot excrete it very well. And I think oral antibiotics are the other very major part of it. Because your normal gut bacteria - this may be too complicated, but your normal gut bacteria tends to demethylate mercury so you excrete it in your stool. Whereas abnormal bacteria like yeast and E. coli will methylate the mercury so you absorb it more readily into your body. So I think it's a - I think those are two of the main factors.
KIRK HAMILTON: So the connection would be is if you had, let's say, you started off with chronic ear infections because the child was on lots of milk products. And then they get the antibiotics repeated rounds, then they would slowly become less able to detoxify because they have altered bacteria in their gut, correct?
DR. JAMES B. ADAMS: Right. And then it's a vicious cycle because mercury then inhibits the production of glutathione and every time any mercury - any glutathione binds to mercury then its excreted in the stool and lost. And so it's a vicious cycle.
KIRK HAMILTON: So if you could give - your study's pretty broad. I mean, could you give like just a synopsis of the significant findings of your study that I mentioned, the "Nutritional and Metabolic Status of Children With Autism Versus Neurotypical Children."
DR. JAMES B. ADAMS: Yeah. That study basically assessed vitamin and mineral levels in kids with autism. We found that for most vitamins and minerals, there weren't major differences, but for a few, biotin in particular was lower in children with autism and we found that kids with autism needed much higher amounts of vitamin B12 and folinic acid. In terms of minerals, we found that they were extremely low in sulfate and there are several other studies that show that, too. And also low in lithium. And we published a previous study that showed that children with autism and their mothers were low in lithium, and low lithium is associated with a wide range of psychiatric disorders such as schizophrenia and aggressive crime like murder. And so that's part of what we found. We also looked at levels of amino acids and found that several of those were lower in children with autism, primarily tryptophan which is needed to be converted to serotonin, an important neurotransmitter, and we also found kids with autism had very high oxidative stress, could be due to toxic metals, could be due to toxins from gut bacteria. We don't know the source, but we know that that was a big problem. And we found that they had low levels of ATP, which is a major fuel for the body and the brain. So those are a quick summary of some of the major things we found. We have a new study hopefully coming out soon that shows that treating with a basic vitamin/mineral supplement resolves almost all of - it greatly improves or normalizes almost all of those abnormalities that we found. So basically, the bottom line for parents is that taking a good vitamin/mineral supplement is very important for children with autism.
KIRK HAMILTON: Now would that have to be a tailored nutritional supplement that came from the testing, or you've actually created one that could work generally and in prevention?
DR. JAMES B. ADAMS: We did a treatment study which again should be published soon in which we found that customized vitamin/mineral supplement that we designed not only improved or normalized many of these different biomarkers, but it also led to behavioral improvements. Just overall improvement, also less tantruming, less hyperactivity, better language, so we saw some good overall improvements as well. And that was in a double-blind placebo controlled study, very rigorous. About a third of the kids didn't benefit much, about a third had mild benefits, and a third just really improved a lot. And we were able to determine which vitamins seemed to be most linked with that degree of improvement and it really boiled down to two. That biotin and vitamin K were the two vitamins that were most strongly associated with predicting who would be improved. In other words, the kids who were low in biotin and that was improved by the supplement, those were the kids that had the most improvement. Well it took me six months to figure out is what was the - what did vitamin K and biotin have in common, and then eventually I realized what they had in common is that they're the only two vitamins that are mostly produced by your gut bacteria. You get about half of them from your gut bacteria, not from the foods you eat, and there aren't any other vitamins like that. It's very interesting that the two gut-derived vitamins were the ones that were the best predictors of who would improve from a vitamin/mineral supplement.
KIRK HAMILTON: I'd like to - we've got a few more minutes here. I'd like to close with kind of like I've got three simple - simple, that actually was a very dumb statement I just made. Vaccines. What would you - advice would you give a young mother who hears about this stuff about how to introduce vaccines into their children? I know it's a controversial area, but do you have some general rules and precautions?
DR. JAMES B. ADAMS: Well first I'd mention a study we did of kids with seizures. We did a national survey of a thousand kids with seizures and we found that of the kids who had regressive autism, 70% of those felt it was seizure related. That the seizures began, autism was associated with vaccinations. So many autism families are very suspicious, but the research is unclear. But I think there are a few things to do that seem wise. I think delaying vaccinations, using a less aggressive schedule than we use in the U.S., a little slower schedule like that used in Japan. I think giving vaccinations one at a time instead of multiple vaccinations. Only vaccinating when you're healthy, and frankly just skipping some vaccines like the hepatitis B vaccine unless a mother has hepatitis B. But the other thing I would really challenge the vaccine industry on is it's very strange that vaccines are given in the same dose to a 2 pound premature child as to a 200-pound football player. There's no other medication you give the same way. I think with vaccines we should adjust the dose to a child's body weight so that a 5-pound child gets a smaller dose than a 100-pound person. I think that's just common sense. And we should remove the preservatives. We should go to single dose vaccines instead of the current multidose vaccines that you have to put high amounts of preservatives in them. There's no need to do that.
KIRK HAMILTON: Great answer. You know, the reason I asked you is we get this asked all the time and I - one of our staff had a preemie child and you know probably now is six months, but probably really three months old, and asked us that question and I actually had about five out of those six or seven, so that makes me feel good. How about prevention if you were - if you could be a czar so to speak and you could start having your effect on pregnant females, and then forward into let's say the first year or two of life. What would you do to help prevent autism?
DR. JAMES B. ADAMS: That's a great question and I'm delighted to see people just beginning to ask that question. There're several risk factors that we're now learning about. I think one of the most important ones is that during a mother's annual physical, it's very common to measure their level of homocysteine. Moms of kids with autism tend to have abnormally high levels. And that's a clue if they have that problem they probably also have a problem with methylation and with glutathione. And if they have both of those problem, a very powerful study by Jill James, showed then it's about 45 times more likely that they will be a mother of a child with autism. And so just the treatment for it is very simple. Just giving a folinic acid and vitamin B12 normalizes homocysteine, which also is a risk factor for heart disease. That's why it's done. So autism mothers tend to be at higher risk, have a higher risk factor there. And I think that alone would dramatically decrease the incidence of autism and also improves the mother's health. I think lithium is an important issue. I think essential fatty acids are important. Many mothers don't get enough seafood. And also I think really reducing the usage of oral antibiotics. I think most pediatricians would agree that oral antibiotics are overused and I think we should take - we should only reserve them for when there's a great need. Certainly not for an ear infection where their benefit is very questionable.
KIRK HAMILTON: How about - then the last question I'd like to wrap up with. Let's say unfortunately a parent right now all of a sudden they find out their child is autistic. And to save maybe some of the pain and struggle that you went through 17 years ago, what would you say would be the fastest way or an organization or organizations to go to get help quickly that would give some hope?
DR. JAMES B. ADAMS: There are a couple of things they can do. On our website autism.asu.edu, we have a summary of biomedical treatments, a short 28-page summary. So if they want to look at biomedical options I think it's a very good thing to do. I'd urge them to look for one-on-one intensive behavioral therapy, 28 to 30 hours a week, supervised by someone who's experienced, who's certified and knows what they're doing. Not just a body. I think those two things would be probably the two most helpful things they could do. I am also very intrigued with relationship development interventions where you coach the parents how to be "super-parents," how to be very interactive and proactive with their child. They can develop a better relationship because I think that socialization is really the core of autism. Autism literally means ‘aloneness' And empowering parents to break through that barrier to reach their children is very important.
KIRK HAMILTON: Can you one more time say slowly the website at the University of Arizona.
DR. JAMES B. ADAMS: Autism dot ASU, short for Arizona State University, dot edu (autism.asu.edu).
KIRK HAMILTON: That's it.
DR. JAMES B. ADAMS: So that if they type that in, that will also lead them - I'm also the president of the Autism Society of Greater Phoenix and our chapter helps hundreds of families, thousands of families with questions.
KIRK HAMILTON: Is there a department of autistic research or an organization at the university, or is this just a -
DR. JAMES B. ADAMS: I direct the ASU Autism Research Program that focuses on biomedical issues, but there are a number of my colleagues here, some in speech, some in psychology, some in special ed, who each look at different aspects of autism.
KIRK HAMILTON: Well Dr. Adams, not only - well first of all, I'm just very thankful because I deal with this all the time and I always want to guide people to real credible people who I think have the pulse of what truly can help people and I think you do that. Two, is I admire you for being a parent 17 years, working so hard to find solutions, and to be a loving parent. It sounds like you're a fabulous one. So thank you very much for being on the show today, and I'd love to have you on again to see, you know, whenever you have a paper come out that just send it to me, you know PDF or something, and I'll get you back on and interview you on the topic. So thank you so much.
DR. JAMES B. ADAMS: Thank you.
KIRK HAMILTON: And I want to thank you, the audience, for being on this edition of Staying Healthy Today Radio. And until next time, Stay and Be Well.
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